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Front Microbiol. 2018 Aug 14;9:1887. doi: 10.3389/fmicb.2018.01887. eCollection 2018.

The .

Frontiers in microbiology

Simona Pepe, Eva Pinatel, Elisabetta Fiore, Simone Puccio, Clelia Peano, Tarcisio Brignoli, Andrea Vannini, Alberto Danielli, Vincenzo Scarlato, Davide Roncarati

Affiliations

  1. Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Bologna, Italy.
  2. Institute of Biomedical Technologies, National Research Council, Milan, Italy.
  3. Humanitas Clinical and Research Center, Milan, Italy.
  4. Institute of Genetic and Biomedical Research, National Research Council, Milan, Italy.

PMID: 30154784 PMCID: PMC6102357 DOI: 10.3389/fmicb.2018.01887

Abstract

The ability of pathogens to perceive environmental conditions and modulate gene expression accordingly is a crucial feature for bacterial survival. In this respect, the heat-shock response, a universal cellular response, allows cells to adapt to hostile environmental conditions and to survive during stress. In the major human pathogen

Keywords: ChIP-seq; HspR repressor; RNA-sequencing; heat-shock response; transcriptome

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