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Temelkova I, Mangarov H, Tronnier M, et al. Eruptive Basaliomas: "Why we have to Perform Surgery?" Or Said Otherwise: "Catch The Metatypical!". Open Access Maced J Med Sci. 2018;6(8):1435-1437doi: 10.3889/oamjms.2018.203.
Temelkova, I., Mangarov, H., Tronnier, M., Terziev, I., & Tchernev, G. (2018). Eruptive Basaliomas: "Why we have to Perform Surgery?" Or Said Otherwise: "Catch The Metatypical!". Open access Macedonian journal of medical sciences, 6(8), 1435-1437. https://doi.org/10.3889/oamjms.2018.203
Temelkova, Ivanka, et al. "Eruptive Basaliomas: "Why we have to Perform Surgery?" Or Said Otherwise: "Catch The Metatypical!"." Open access Macedonian journal of medical sciences vol. 6,8 (2018): 1435-1437. doi: https://doi.org/10.3889/oamjms.2018.203
Temelkova I, Mangarov H, Tronnier M, Terziev I, Tchernev G. Eruptive Basaliomas: "Why we have to Perform Surgery?" Or Said Otherwise: "Catch The Metatypical!". Open Access Maced J Med Sci. 2018 Jul 30;6(8):1435-1437. doi: 10.3889/oamjms.2018.203. eCollection 2018 Aug 20. PMID: 30159071; PMCID: PMC6108802.
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Open Access Maced J Med Sci. 2018 Jul 30;6(8):1435-1437. doi: 10.3889/oamjms.2018.203. eCollection 2018 Aug 20.

Eruptive Basaliomas: "Why we have to Perform Surgery?" Or Said Otherwise: "Catch The Metatypical!".

Open access Macedonian journal of medical sciences

Ivanka Temelkova, Hristo Mangarov, Michael Tronnier, Ivan Terziev, Georgi Tchernev

Affiliations

  1. Medical Institute of Ministry of Interior (MVR), Department of Dermatology, Venereology and Dermatologic Surgery, Sofia, Bulgaria.
  2. Helios Klinikum GMBH, Dermatology, Venereology and Allergology, Hildesheim, Germany.
  3. Universitetska Mnogoprofilno Bolnitsa za Aktivno Lechenie Tsaritsa Yoanna, Common and Clinical Pathology, Sofia, Bulgaria.
  4. Onkoderma, Policlinic for Dermatology and Dermatologic Surgery General Skobelev 26, Sofia, Bulgaria.

PMID: 30159071 PMCID: PMC6108802 DOI: 10.3889/oamjms.2018.203

Abstract

BACKGROUND: Keratinocyte cancers are malignant diseases with a broad incidence of spread which tends to increase during the last couple of decades. The solar radiation plays a dominant role in the occurrence of BCC, but certain genetic phenotypes appear to be risky from an etiological point of view. Metatypical basal cell carcinoma (MTBCC) is a rare variant of BCC which combines the clinical and histological characteristics of BCC and SCC. Clinically they are indistinguishable from the conventional BCC, and only the histological examination can differentiate them. The MTBCC is a histological subtype which is considered more aggressive due to its ability to produce local recurrences or distant metastases.

CASE REPORT: We present a 44-year old patient with multiple BCCs disseminated on the face and body. The biopsy established mixed type histology: three metatypical and four solid BCCs. The lesions were removed via elliptical excision with a field of operational security of 0.5 cm in all directions.

CONCLUSIONS: The eruptive (multiple) BCCs are a challenge about the choice of a therapy option. This is because clinically completely identical tumours show different histopathological characteristics, namely those with a tendency to metastasise. Having in mind one of the hypotheses of metatypical BCC emergence - the improper or inadequate radiotherapy (as a choice of therapy) could trigger the transition of a conventional tumour to a metastasising one, the surgical treatment appears to be the most secure treatment method.

Keywords: Basal cell carcinoma; Metatypical basal cell carcinoma; Radiation; Surgery

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