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Vilcacundo R, Barrio DA, Piñuel L, et al. Inhibition of Lipid Peroxidation of Kiwicha (. Plants (Basel). 2018;7(3)doi: 10.3390/plants7030069.
Vilcacundo, R., Barrio, D. A., Piñuel, L., Boeri, P., Tombari, A., Pinto, A., Welbaum, J., Hernández-Ledesma, B., & Carrillo, W. (2018). Inhibition of Lipid Peroxidation of Kiwicha (. Plants (Basel, Switzerland), 7(3), . https://doi.org/10.3390/plants7030069
Vilcacundo, Rubén, et al. "Inhibition of Lipid Peroxidation of Kiwicha (." Plants (Basel, Switzerland) vol. 7,3 (2018). doi: https://doi.org/10.3390/plants7030069
Vilcacundo R, Barrio DA, Piñuel L, Boeri P, Tombari A, Pinto A, Welbaum J, Hernández-Ledesma B, Carrillo W. Inhibition of Lipid Peroxidation of Kiwicha (. Plants (Basel). 2018 Sep 02;7(3). doi: 10.3390/plants7030069. PMID: 30200527; PMCID: PMC6161091.
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Plants (Basel). 2018 Sep 02;7(3). doi: 10.3390/plants7030069.

Inhibition of Lipid Peroxidation of Kiwicha (.

Plants (Basel, Switzerland)

Rubén Vilcacundo, Daniel Alejandro Barrio, Lucrecia Piñuel, Patricia Boeri, Andrea Tombari, Adelita Pinto, James Welbaum, Blanca Hernández-Ledesma, Wilman Carrillo

Affiliations

  1. Laboratory of Functional Foods, Faculty of Foods Sciences and Engineering, Technical University of Ambato, Av. Los Chasquis y Rio Payamino, Campus Huachi, Ambato 1801334, Ecuador. [email protected].
  2. CIT-RIO NEGRO Sede Atlántica, Universidad Nacional de Rio Negro (UNRN-CONICET), Don Bosco y Leloir s/n CP 8500, Rio Negro Viedma, Argentina. [email protected].
  3. CIT-RIO NEGRO Sede Atlántica, Universidad Nacional de Rio Negro (UNRN-CONICET), Don Bosco y Leloir s/n CP 8500, Rio Negro Viedma, Argentina. [email protected].
  4. CIT-RIO NEGRO Sede Atlántica, Universidad Nacional de Rio Negro (UNRN-CONICET), Don Bosco y Leloir s/n CP 8500, Rio Negro Viedma, Argentina. [email protected].
  5. CIT-RIO NEGRO Sede Atlántica, Universidad Nacional de Rio Negro (UNRN-CONICET), Don Bosco y Leloir s/n CP 8500, Rio Negro Viedma, Argentina. [email protected].
  6. Department of Research, Faculty of Health Sciences, Technical University of Babahoyo, Av. Universitaria Km 21/2 Av. Montalvo., Babahoyo 120301, Ecuador. [email protected].
  7. Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79413, USA. [email protected].
  8. Research Institute of Food Science (CIAL-CSIC-UAM), Nicolás Cabrera 9, 28049 Madrid, Spain. [email protected].
  9. Department of Research, Faculty of Health Sciences, Technical University of Babahoyo, Av. Universitaria Km 21/2 Av. Montalvo., Babahoyo 120301, Ecuador. [email protected].

PMID: 30200527 PMCID: PMC6161091 DOI: 10.3390/plants7030069

Abstract

Amaranth protein concentrate (APC) was hydrolyzed under in vitro gastrointestinal conditions. APC proteins were partially degraded by pepsin at pHs 1.2, 2.0, and 3.2. During the intestinal phase (pepsin/pancreatin enzymes at pH 7.0), no polypeptide bands were observed in the gel, suggesting the susceptibility of amaranth proteins to the action of digestive enzymes. The potent in vitro inhibition of lipid peroxidation, shown by the gastric and intestinal digests, was confirmed in the zebrafish larvae, with a 72.86% reduction in oxidation of lipids in the presence of the gastric hydrolysate at pH 2.0, compared to a 95.72% reduction in the presence of the gastrointestinal digest. APC digests were capable of reducing reactive oxygen species (ROS) production in the zebrafish embryo model with a value of fluorescence of 52.5% for the gastric hydrolysate, and 48.4% for the intestinal hydrolysate.

Keywords: kiwicha; lipid peroxidation; protein concentrate; simulated gastrointestinal digestion; zebrafish embryos

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