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Henry N, Baker BG, Iyer S. Frey's syndrome following a facial burn treated with botulinum toxin. Ann Burns Fire Disasters. 2018;31(1):47-48
Henry, N., Baker, B. G., & Iyer, S. (2018). Frey's syndrome following a facial burn treated with botulinum toxin. Annals of burns and fire disasters, 31(1), 47-48.
Henry, N, et al. "Frey's syndrome following a facial burn treated with botulinum toxin." Annals of burns and fire disasters vol. 31,1 (2018): 47-48.
Henry N, Baker BG, Iyer S. Frey's syndrome following a facial burn treated with botulinum toxin. Ann Burns Fire Disasters. 2018 Mar 31;31(1):47-48. PMID: 30174572; PMCID: PMC6116648.
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Ann Burns Fire Disasters. 2018 Mar 31;31(1):47-48.

Frey's syndrome following a facial burn treated with botulinum toxin.

Annals of burns and fire disasters

N Henry, B G Baker, S Iyer

Affiliations

  1. Royal Preston Hospital, Preston, UK.

PMID: 30174572 PMCID: PMC6116648

Abstract

Frey's syndrome occurs as a result of damage to the auriculotemporal nerve, which causes inappropriate regeneration of damaged parasympathetic fibres to salivary glands to innervate the sympathetic receptors of sweat glands in the face. The symptoms are pathological flushing and sweating with gustatory stimuli. It most commonly occurs following parotid surgery and has not previously been reported following burn injury. We present a 50-year-old man who sustained 1% TBSA full thickness burn to the right side of his face as a child. This was excised and reconstructed with skin grafts as well as further revision procedures in his adult life. He incidentally reported copious amounts of gustatory sweating over his right temple region that had been present since his initial injury, occurring prior to any reconstruction, consistent with Frey's syndrome. This was confirmed with a starch iodine test, and successfully treated with Botulinum toxin injections post reconstruction. This case is the first report of Frey's syndrome following burn injury. We highlight the potential development of Frey's syndrome following facial burns, even in the reconstructed area. Botulinum toxin treatment remains effective.

Keywords: Frey’s syndrome; botulinum toxin; facial burn

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