Display options
Share it on

Am J Lifestyle Med. 2016 Feb 15;10(3):174-177. doi: 10.1177/1559827616631723. eCollection 2016.

Immune Function: Impact of Exercise and Nutritional Interventions.

American journal of lifestyle medicine

Marian L Kohut

Affiliations

  1. Department of Kinesiology/Immunobiology Program, Iowa State University, Ames, Iowa.

PMID: 30202270 PMCID: PMC6124960 DOI: 10.1177/1559827616631723

Abstract

This article provides a brief commentary on the accompanying article, "Nutrition and Physical Activity Interventions to Improve Immunity" by Davison, Kehaya, and Jones. The article reviews the evidence on physical exercise and/or nutrition in modulating immune response, with a specific focus on the prevention of respiratory infection. Given the large scope of the review, an overview of current findings is presented, rather than in-depth discussions, and the nutritional strategies discussed tend to focus on the strategies that have been studied in the context of exercise. Some further insight is provided in the commentary on potential mechanisms that may explain the benefits of exercise, a brief discussion on the impact of obesity and host defense, and future directions for research. In general, the article sufficiently describes the current evidence, and draws appropriate conclusions based on the evidence presented. The article is recommended for audiences that have limited background on these topics, and for those who are familiar with this line of research.

Keywords: Respiratory infection; exercise; immunity; nutrition

References

  1. J Infect Dis. 2009 Nov 1;200(9):1434-42 - PubMed
  2. Nat Med. 2012 Jan 29;18(2):274-80 - PubMed
  3. Clin Infect Dis. 2011 Feb 1;52(3):301-12 - PubMed
  4. J Appl Physiol (1985). 2004 Aug;97(2):491-8 - PubMed
  5. J Gerontol A Biol Sci Med Sci. 2002 Sep;57(9):M557-62 - PubMed
  6. Vaccine. 2007 Jun 28;25(27):5086-96 - PubMed
  7. J Nutr. 2009 Aug;139(8):1588-94 - PubMed
  8. J Appl Physiol (1985). 2013 May 15;114(10):1413-20 - PubMed
  9. Arch Intern Med. 2003 Feb 24;163(4):487-94 - PubMed
  10. Exerc Immunol Rev. 2006;12:97-111 - PubMed
  11. Vaccine. 2008 Oct 3;26(42):5407-15 - PubMed
  12. J Appl Physiol (1985). 2014 Nov 1;117(9):998-1007 - PubMed
  13. Vaccine. 2009 Apr 21;27(18):2418-25 - PubMed
  14. Int J Obes (Lond). 2012 Aug;36(8):1072-7 - PubMed
  15. Autoimmunity. 2006 Mar;39(2):137-41 - PubMed
  16. Immunity. 2008 Jul 18;29(1):101-13 - PubMed
  17. PLoS Med. 2011 Jul;8(7):e1001053 - PubMed
  18. J Immunol. 2011 Dec 1;187(11):5510-4 - PubMed
  19. Vaccine. 2004 Jun 2;22(17-18):2298-306 - PubMed
  20. Brain Behav Immun. 2014 Jul;39:33-41 - PubMed
  21. J Immunol. 2015 Jul 1;195(1):203-9 - PubMed
  22. J Appl Physiol (1985). 2007 Mar;102(3):1090-8 - PubMed
  23. JAMA. 1985 Dec 13;254(22):3187-9 - PubMed
  24. PLoS One. 2015 Jun 25;10(6):e0129713 - PubMed
  25. Immunity. 2013 Apr 18;38(4):633-43 - PubMed
  26. Crit Care. 2012 Oct 18;16(5):R199 - PubMed
  27. Proc Nutr Soc. 2012 May;71(2):298-306 - PubMed
  28. J Immunol. 2006 May 15;176(10):6333-9 - PubMed
  29. Cochrane Database Syst Rev. 2015 Jun 16;(6):CD010596 - PubMed

Publication Types