J Res Med Sci. 2018 Aug 23;23:76. doi: 10.4103/jrms.JRMS_627_17. eCollection 2018.
How may Doppler indices help in the differentiation of obstructive from nonobstructive hydronephrosis?.
Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences
Maryam Riahinezhad, Amir Hossein Sarrami, Alaleh Gheisari, Omid Shafaat, Alireza Merikhi, Mehdi Karami, Maryam Farghadani, Masoud Moslehi
Affiliations
Affiliations
- Department of Radiology, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.
- Department of Pediatrics, Emam Hossein Children Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.
- Department of Neurointerventional Radiology, Isfahan University of Medical Sciences, Isfahan, Iran.
- Department of Medical Physics, Isfahan University of Medical Sciences, Isfahan, Iran.
PMID: 30181758
PMCID: PMC6116660 DOI: 10.4103/jrms.JRMS_627_17
Abstract
BACKGROUND: We assess the potency of different Doppler indices in the differentiation of obstructive and nonobstructive hydronephrosis.
MATERIALS AND METHODS: In this study, infants and children who were referred for the evaluation of unilateral hydronephrosis were enrolled. Ultrasonography for the assessment of the degree of hydronephrosis and a voiding cystourethrogram for the exclusion of vesicoureteral reflux was performed. Then, Doppler ultrasonography was done for both kidneys of each patient using four classic Doppler indices as well as the difference (delta) of each index between to kidneys. Diuretic renography with 99 mTc-ethylene dicysteine (99 mTc-EC) was performed for each patient.
RESULTS: Thirty-nine patients met the inclusion criteria. After diuretic renography, 29 (74.35%) patients had shown a nonobstructive pattern, and ten (25.65%) patients had a partial (intermediate) or complete obstruction. Using receiver operating characteristic (ROC) curve, none of the classic indices of Doppler duplex (i.e., resistive index [RI], resistance index, end diastolic velocity, and peak systolic velocity) had the ability to make a difference between obstructive and nonobstructive hydronephrosis. However, by calculating the difference (delta) of these indices between two kidneys of each patient, delta RI could differentiate the nonobstructive condition, significantly (
CONCLUSION: This study shows that RI ratio and delta RI with a high specificity could differentiate nonobstructive hydronephrosis and therefore it is a promising way to use especially in the follow-up of children with hydronephrosis.
Keywords: Doppler; hydronephrosis; pediatric; radioisotope renography; ultrasonography; ureteropelvic junction obstruction
Conflict of interest statement
There are no conflicts of interest.
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