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Front Oncol. 2018 Sep 20;8:382. doi: 10.3389/fonc.2018.00382. eCollection 2018.

Detection of the .

Frontiers in oncology

Soheil Zorofchian, Guangrong Lu, Jay-Jiguang Zhu, Dzifa Y Duose, Justin Windham, Yoshua Esquenazi, Leomar Y Ballester

Affiliations

  1. Department of Pathology and Laboratory Medicine, University of Texas Health Science Center, Houston, TX, United States.
  2. Vivian L. Smith Department of Neurosurgery, University of Texas Health Science Center, Houston, TX, United States.
  3. Department of Translational Molecular Pathology, UT MD Anderson Cancer Center, Houston, TX, United States.

PMID: 30294590 PMCID: PMC6158312 DOI: 10.3389/fonc.2018.00382

Abstract

Primary Central Nervous System Lymphoma (PCNSL) and Metastatic (or Secondary) Central Nervous System Lymphoma (MCNSL) are rare central nervous system (CNS) malignancies that exhibit aggressive clinical behavior and have a poor prognosis. The majority of CNS lymphomas are histologically classified as diffuse large-B cell lymphoma (DLBCL). DLBCL harbors a high frequency of mutations in

Keywords: CSF; MYD88; central nervous system lymphoma; cerebrospinal fluid; digital droplet PCR; liquid biopsy

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