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Tosello V, Milani G, Martines A, et al. A Novel t(8;14)(q24;q11) Rearranged Human Cell Line as a Model for Mechanistic and Drug Discovery Studies of NOTCH1-Independent Human T-Cell Leukemia. Cells. 2018;7(10)doi: 10.3390/cells7100160.
Tosello, V., Milani, G., Martines, A., Macri, N., Van Loocke, W., Matthijssens, F., Buldini, B., Minuzzo, S., Bongiovanni, D., Schumacher, R. F., Amadori, A., Van Vlierberghe, P., & Piovan, E. (2018). A Novel t(8;14)(q24;q11) Rearranged Human Cell Line as a Model for Mechanistic and Drug Discovery Studies of NOTCH1-Independent Human T-Cell Leukemia. Cells, 7(10), . https://doi.org/10.3390/cells7100160
Tosello, Valeria, et al. "A Novel t(8;14)(q24;q11) Rearranged Human Cell Line as a Model for Mechanistic and Drug Discovery Studies of NOTCH1-Independent Human T-Cell Leukemia." Cells vol. 7,10 (2018). doi: https://doi.org/10.3390/cells7100160
Tosello V, Milani G, Martines A, Macri N, Van Loocke W, Matthijssens F, Buldini B, Minuzzo S, Bongiovanni D, Schumacher RF, Amadori A, Van Vlierberghe P, Piovan E. A Novel t(8;14)(q24;q11) Rearranged Human Cell Line as a Model for Mechanistic and Drug Discovery Studies of NOTCH1-Independent Human T-Cell Leukemia. Cells. 2018 Oct 09;7(10). doi: 10.3390/cells7100160. PMID: 30304769; PMCID: PMC6209910.
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Cells. 2018 Oct 09;7(10). doi: 10.3390/cells7100160.

A Novel t(8;14)(q24;q11) Rearranged Human Cell Line as a Model for Mechanistic and Drug Discovery Studies of NOTCH1-Independent Human T-Cell Leukemia.

Cells

Valeria Tosello, Gloria Milani, Annalisa Martines, Nadia Macri, Wouder Van Loocke, Filip Matthijssens, Barbara Buldini, Sonia Minuzzo, Deborah Bongiovanni, Richard Fabian Schumacher, Alberto Amadori, Pieter Van Vlierberghe, Erich Piovan

Affiliations

  1. UOC Immunologia e Diagnostica Molecolare Oncologica, Istituto Oncologico Veneto-IRCCS, Padova 35128, Italy. [email protected].
  2. Department of Biomolecular Medicine, Ghent University, Ghent 9000, Belgium. [email protected].
  3. Cancer Research Institute Ghent (CRIG), Ghent 9000, Belgium. [email protected].
  4. UOC Immunologia e Diagnostica Molecolare Oncologica, Istituto Oncologico Veneto-IRCCS, Padova 35128, Italy. [email protected].
  5. UOC Immunologia e Diagnostica Molecolare Oncologica, Istituto Oncologico Veneto-IRCCS, Padova 35128, Italy. [email protected].
  6. Department of Biomolecular Medicine, Ghent University, Ghent 9000, Belgium. [email protected].
  7. Cancer Research Institute Ghent (CRIG), Ghent 9000, Belgium. [email protected].
  8. Department of Biomolecular Medicine, Ghent University, Ghent 9000, Belgium. [email protected].
  9. Cancer Research Institute Ghent (CRIG), Ghent 9000, Belgium. [email protected].
  10. Dipartimento di Salute della Donna e del Bambino, Università degli Studi di Padova, Padova 35128, Italy. [email protected].
  11. Dipartimento di Scienze Chirurgiche, Oncologiche e Gastroenterologiche, Universita' degli Studi di Padova, Padova 35128, Italy. [email protected].
  12. Dipartimento di Scienze Chirurgiche, Oncologiche e Gastroenterologiche, Universita' degli Studi di Padova, Padova 35128, Italy. [email protected].
  13. Pediatric Oncology Unit of Spedali Civili di Brescia, Brescia 25123, Italy. [email protected].
  14. UOC Immunologia e Diagnostica Molecolare Oncologica, Istituto Oncologico Veneto-IRCCS, Padova 35128, Italy. [email protected].
  15. Dipartimento di Scienze Chirurgiche, Oncologiche e Gastroenterologiche, Universita' degli Studi di Padova, Padova 35128, Italy. [email protected].
  16. Department of Biomolecular Medicine, Ghent University, Ghent 9000, Belgium. [email protected].
  17. Cancer Research Institute Ghent (CRIG), Ghent 9000, Belgium. [email protected].
  18. UOC Immunologia e Diagnostica Molecolare Oncologica, Istituto Oncologico Veneto-IRCCS, Padova 35128, Italy. [email protected].
  19. Dipartimento di Scienze Chirurgiche, Oncologiche e Gastroenterologiche, Universita' degli Studi di Padova, Padova 35128, Italy. [email protected].

PMID: 30304769 PMCID: PMC6209910 DOI: 10.3390/cells7100160

[No abstract available.]

Keywords: BRD4 inhibition; MYC-translocated leukemia; NOTCH1-independent; T-lineage acute lymphoblastic leukemia; super-enhancers; targeted therapy

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