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Zhuanping Z, Rifang L, Qing C, et al. The Association between . Iran J Public Health. 2018;47(9):1272-1280
Zhuanping, Z., Rifang, L., Qing, C., & Sidong, C. (2018). The Association between . Iranian journal of public health, 47(9), 1272-1280.
Zhuanping, Zeng, et al. "The Association between ." Iranian journal of public health vol. 47,9 (2018): 1272-1280.
Zhuanping Z, Rifang L, Qing C, Sidong C. The Association between . Iran J Public Health. 2018 Sep;47(9):1272-1280. PMID: 30320001; PMCID: PMC6174046.
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Iran J Public Health. 2018 Sep;47(9):1272-1280.

The Association between .

Iranian journal of public health

Zeng Zhuanping, Liao Rifang, Chen Qing, Chen Sidong

Affiliations

  1. School of Public Health, Guangdong Pharmaceutical University, Guangzhou 510310, China.
  2. Dept. of Pharmacy, Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China.
  3. Dept. of Epidemiology, School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou 510515, China.

PMID: 30320001 PMCID: PMC6174046

Abstract

BACKGROUND: To examine whether polymorphisms of

METHODS: In this community-based, case-control study, 568 subjects (284 patients and 284 controls) were enrolled in a community located in northern Guangzhou, China. The four polymorphisms of

RESULTS: The rs4746720 CC+TT genotype had higher risk compared with CT genotype to develop T2DM [odds ratio (OR) =1.42, 95% confidence interval (CI) = 1.02-1.97]. The subjects with rs4746720 CC+TT genotype and eat sugar food over 30g per day increased the risk of T2DM to 2.22(1.21-4.06) times. The subjects with rs4746720 CC+TT genotype and smoking increased the risk of T2DM to 1.65 (1.10-2.47) times. The unhealthy eating habits such as red meat, salty food, use animal fat yielded higher risks of T2DM, the OR of risk of T2DM was 2.89 (1.38-6.01), 2.73 (1.61-4.64) and 27.91(9.24-84.32) respectively. However, the milk, soy, white meat, vegetables and low-salt diet decreased the risk of T2DM, the OR of risk of T2DM was 0.51 (0.29-0.88), 0.43 (0.26-0.74), 0.51(0.32-0.83), 0.21(0.10-0.44), 0.28(0.12-0.65), 0.35(0.21-0.51) respectively.

CONCLUSION: Variants in

Keywords: China; Dietary; Sirtuin 1; Type 2 diabetes mellitus

Conflict of interest statement

Conflict of interest The authors declare that there is no conflict of interests.

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