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J Cardiol Cases. 2017 Mar 06;15(4):125-128. doi: 10.1016/j.jccase.2016.12.004. eCollection 2017 Apr.

A case of life-threatening supraventricular tachycardia storm associated with theophylline toxicity.

Journal of cardiology cases

Keishi Ichikawa, Tadashi Wada, Takahiro Nishihara, Masahiro Tsuji, Atsushi Mori, Fumi Yokohama, Daiji Hasegawa, Kenji Kawamoto, Machiko Tanakaya, Yusuke Katyama, Satoru Sakuragi, Hiroshi Ito

Affiliations

  1. Department of Cardiovascular Medicine, Iwakuni Clinical Center, Iwakuni, Japan.
  2. Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Okayama, Japan.

PMID: 30279758 PMCID: PMC6135038 DOI: 10.1016/j.jccase.2016.12.004

Abstract

A 76-year-old man taking theophylline was admitted to our hospital with congestive heart failure and supraventricular tachycardia (SVT). After admission, he developed cardiogenic shock as a result of SVT storm, which was refractory to medical treatment including adenosine and electrical cardioversion. The serum theophylline concentration at admission was identified as toxic. Therefore, theophylline toxicity was considered as a major cause of the SVT storm. Hemodynamic stability was achieved by using mechanical circulatory support. Additionally, continuous hemodiafiltration was performed to remove theophylline, and it was effective for suppression of SVT. The patient was successfully weaned off mechanical circulatory support. After the patient's general status had improved, an electrophysiological study was performed, and it showed orthodromic atrioventricular reentrant tachycardia with a right free wall accessory pathway. Radiofrequency catheter ablation was successfully performed. <

Keywords: Mechanical circulatory support; Supraventricular tachycardia storm; Theophylline toxicity

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