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de Mey S, Jiang H, Corbet C, et al. Antidiabetic Biguanides Radiosensitize Hypoxic Colorectal Cancer Cells Through a Decrease in Oxygen Consumption. Front Pharmacol. 2018;9:1073doi: 10.3389/fphar.2018.01073.
de Mey, S., Jiang, H., Corbet, C., Wang, H., Dufait, I., Law, K., Bastien, E., Verovski, V., Gevaert, T., Feron, O., & De Ridder, M. (2018). Antidiabetic Biguanides Radiosensitize Hypoxic Colorectal Cancer Cells Through a Decrease in Oxygen Consumption. Frontiers in pharmacology, 91073. https://doi.org/10.3389/fphar.2018.01073
de Mey, Sven, et al. "Antidiabetic Biguanides Radiosensitize Hypoxic Colorectal Cancer Cells Through a Decrease in Oxygen Consumption." Frontiers in pharmacology vol. 9 (2018): 1073. doi: https://doi.org/10.3389/fphar.2018.01073
de Mey S, Jiang H, Corbet C, Wang H, Dufait I, Law K, Bastien E, Verovski V, Gevaert T, Feron O, De Ridder M. Antidiabetic Biguanides Radiosensitize Hypoxic Colorectal Cancer Cells Through a Decrease in Oxygen Consumption. Front Pharmacol. 2018 Oct 03;9:1073. doi: 10.3389/fphar.2018.01073. eCollection 2018. PMID: 30337872; PMCID: PMC6178882.
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Front Pharmacol. 2018 Oct 03;9:1073. doi: 10.3389/fphar.2018.01073. eCollection 2018.

Antidiabetic Biguanides Radiosensitize Hypoxic Colorectal Cancer Cells Through a Decrease in Oxygen Consumption.

Frontiers in pharmacology

Sven de Mey, Heng Jiang, Cyril Corbet, Hui Wang, Inès Dufait, Kalun Law, Estelle Bastien, Valeri Verovski, Thierry Gevaert, Olivier Feron, Mark De Ridder

Affiliations

  1. Department of Radiotherapy, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium.
  2. Pole of Pharmacology and Therapeutics, Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain, Brussels, Belgium.
  3. Laboratory of Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium.

PMID: 30337872 PMCID: PMC6178882 DOI: 10.3389/fphar.2018.01073

[No abstract available.]

Keywords: colorectal cancer; hypoxic radiosensitivity; metformin; mitochondrial complex I; oxygen consumption rate; phenformin

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