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Lamy R, Chan E, Lee OT, et al. 880 kHz ultrasound treatment for drug delivery to the vitreous humor. Am J Transl Res. 2018;10(10):3162-3170
Lamy, R., Chan, E., Lee, O. T., Phone, A., Salgaonkar, V. A., Diederich, C. J., & Stewart, J. M. (2018). 880 kHz ultrasound treatment for drug delivery to the vitreous humor. American journal of translational research, 10(10), 3162-3170.
Lamy, Ricardo, et al. "880 kHz ultrasound treatment for drug delivery to the vitreous humor." American journal of translational research vol. 10,10 (2018): 3162-3170.
Lamy R, Chan E, Lee OT, Phone A, Salgaonkar VA, Diederich CJ, Stewart JM. 880 kHz ultrasound treatment for drug delivery to the vitreous humor. Am J Transl Res. 2018 Oct 15;10(10):3162-3170. eCollection 2018. PMID: 30416658; PMCID: PMC6220232.
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Am J Transl Res. 2018 Oct 15;10(10):3162-3170. eCollection 2018.

880 kHz ultrasound treatment for drug delivery to the vitreous humor.

American journal of translational research

Ricardo Lamy, Elliot Chan, On-Tat Lee, Audrey Phone, Vasant A Salgaonkar, Chris J Diederich, Jay M Stewart

Affiliations

  1. Department of Ophthalmology, University of California San Francisco, CA, USA.
  2. Department of Radiation Oncology, University of California San Francisco, CA, USA.

PMID: 30416658 PMCID: PMC6220232

Abstract

Clinical management of many chronic ophthalmological disorders requires direct delivery of drugs into the vitreous. There is an important need to investigate novel needle-less alternatives to deliver drugs to the vitreous. The purpose of this study is to assess the effects of a needle-less system using ultrasound to enhance vitreal delivery of small molecules through the sclera in an

Keywords: Ultrasonic; drug delivery systems; intravitreal; sclera; vitreous

Conflict of interest statement

None.

References

  1. Expert Opin Drug Deliv. 2004 Nov;1(1):37-56 - PubMed
  2. Drug Discov Today. 2004 Aug 1;9(15):670-6 - PubMed
  3. J Ther Ultrasound. 2014 Mar 31;2:6 - PubMed
  4. Clin Exp Ophthalmol. 2013 Jul;41(5):500-7 - PubMed
  5. Ophthalmology. 2014 Jan;121(1):67-71 - PubMed
  6. Int J Pharm. 2010 Nov 30;401(1-2):16-24 - PubMed
  7. Oftalmol Zh. 1970;25(7):502-6 - PubMed
  8. Eur J Pharm Biopharm. 2014 Sep;88(1):104-15 - PubMed
  9. Int J Retina Vitreous. 2017 Jul 3;3:23 - PubMed
  10. Ann Biomed Eng. 2012 May;40(5):1182-91 - PubMed
  11. Retina. 2011 Sep;31(8):1449-69 - PubMed
  12. PLoS One. 2016 Nov 2;11(11):e0165520 - PubMed
  13. Retina. 2015 Aug;35(8):1647-55 - PubMed
  14. Ultrasound Med Biol. 2014 Jun;40(6):1216-27 - PubMed
  15. Oftalmol Zh. 1974;29(2):114-8 - PubMed
  16. Retina. 2012 Apr;32(4):696-700 - PubMed
  17. Cochrane Database Syst Rev. 2014 May 01;(5):CD007325 - PubMed
  18. Am J Ophthalmol. 2015 Oct;160(4):843-4 - PubMed
  19. Cochrane Database Syst Rev. 2014 Aug 29;(8):CD005139 - PubMed
  20. Micron. 2001 Apr;32(3):261-72 - PubMed
  21. Invest Ophthalmol Vis Sci. 2006 Feb;47(2):558-64 - PubMed
  22. Exp Eye Res. 1993 Jan;56(1):17-24 - PubMed
  23. Invest Ophthalmol Vis Sci. 2000 Apr;41(5):1181-5 - PubMed
  24. Int J Hyperthermia. 2012;28(4):405-18 - PubMed
  25. J Ultrasound Med. 2011 May;30(5):714-34 - PubMed
  26. Drug Des Devel Ther. 2014 Nov 28;8:2373-5 - PubMed
  27. Cornea. 2004 Nov;23(8):804-11 - PubMed
  28. Invest Ophthalmol Vis Sci. 2013 Jun 26;54(6):4358-65 - PubMed
  29. Invest Ophthalmol Vis Sci. 2013 Aug 28;54(8):5908-12 - PubMed
  30. Eye (Lond). 2014 May;28(5):510-20 - PubMed

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