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Shavit E, Alavi A, Limacher JJ, et al. Angiosarcoma complicating lower leg elephantiasis in a male patient: An unusual clinical complication, case report and literature review. SAGE Open Med Case Rep. 2018;6:2050313X18796343doi: 10.1177/2050313X18796343.
Shavit, E., Alavi, A., Limacher, J. J., & Sibbald, R. G. (2018). Angiosarcoma complicating lower leg elephantiasis in a male patient: An unusual clinical complication, case report and literature review. SAGE open medical case reports, 62050313X18796343. https://doi.org/10.1177/2050313X18796343
Shavit, Eran, et al. "Angiosarcoma complicating lower leg elephantiasis in a male patient: An unusual clinical complication, case report and literature review." SAGE open medical case reports vol. 6 (2018): 2050313X18796343. doi: https://doi.org/10.1177/2050313X18796343
Shavit E, Alavi A, Limacher JJ, Sibbald RG. Angiosarcoma complicating lower leg elephantiasis in a male patient: An unusual clinical complication, case report and literature review. SAGE Open Med Case Rep. 2018 Oct 30;6:2050313X18796343. doi: 10.1177/2050313X18796343. eCollection 2018. PMID: 30397474; PMCID: PMC6207953.
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SAGE Open Med Case Rep. 2018 Oct 30;6:2050313X18796343. doi: 10.1177/2050313X18796343. eCollection 2018.

Angiosarcoma complicating lower leg elephantiasis in a male patient: An unusual clinical complication, case report and literature review.

SAGE open medical case reports

Eran Shavit, Afsaneh Alavi, James J Limacher, R Gary Sibbald

Affiliations

  1. Division of Dermatology, Department of Medicine, Women's College Hospital, University of Toronto, Toronto, ON, Canada.

PMID: 30397474 PMCID: PMC6207953 DOI: 10.1177/2050313X18796343

Abstract

Chronic lymphedema is rarely complicated by an angiosarcoma. Angiosarcoma superimposed on chronic lymphedema (Stewart-Treves syndrome) is usually seen post breast cancer surgery accompanied by lymph node resection of the axilla. This is a case report of a 59-year-old male patient with elephantiasis that developed an angiosarcoma of the lower leg. He died a month after the diagnostic biopsy was obtained. This is a rare multifocal tumor in a male with an unusual lower leg location. We reviewed the literature and the need to differentiate this often deadly lesion from a Kaposi's sarcoma.

Keywords: Elephantiasis; Kaposi’s sarcoma; Stewart–Treves syndrome; angiosarcoma; lower extremity lymphedema

Conflict of interest statement

Declaration of conflicting interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship and/or publication of this article.

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