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Heuch I, Heuch I, Hagen K, et al. Is chronic low back pain a risk factor for diabetes? The Nord-Trøndelag Health Study. BMJ Open Diabetes Res Care. 2018;6(1):e000569doi: 10.1136/bmjdrc-2018-000569.
Heuch, I., Heuch, I., Hagen, K., Sørgjerd, E. P., Åsvold, B. O., & Zwart, J. A. (2018). Is chronic low back pain a risk factor for diabetes? The Nord-Trøndelag Health Study. BMJ open diabetes research & care, 6(1), e000569. https://doi.org/10.1136/bmjdrc-2018-000569
Heuch, Ingrid, et al. "Is chronic low back pain a risk factor for diabetes? The Nord-Trøndelag Health Study." BMJ open diabetes research & care vol. 6,1 (2018): e000569. doi: https://doi.org/10.1136/bmjdrc-2018-000569
Heuch I, Heuch I, Hagen K, Sørgjerd EP, Åsvold BO, Zwart JA. Is chronic low back pain a risk factor for diabetes? The Nord-Trøndelag Health Study. BMJ Open Diabetes Res Care. 2018 Oct 23;6(1):e000569. doi: 10.1136/bmjdrc-2018-000569. eCollection 2018. PMID: 30397493; PMCID: PMC6203062.
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BMJ Open Diabetes Res Care. 2018 Oct 23;6(1):e000569. doi: 10.1136/bmjdrc-2018-000569. eCollection 2018.

Is chronic low back pain a risk factor for diabetes? The Nord-Trøndelag Health Study.

BMJ open diabetes research & care

Ingrid Heuch, Ivar Heuch, Knut Hagen, Elin Pettersen Sørgjerd, Bjørn Olav Åsvold, John-Anker Zwart

Affiliations

  1. Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.
  2. Department of Mathematics, University of Bergen, Bergen, Norway.
  3. Department of Neuromedicine and Movement Science, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
  4. Norwegian Advisory Unit on Headaches, St. Olavs University Hospital, Trondheim, Norway.
  5. Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, HUNT Research Centre, NTNU, Norwegian University of Science and Technology, Levanger, Norway.
  6. Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, K.G. Jebsen Center for Genetic Epidemiology, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
  7. Department of Endocrinology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
  8. Faculty of Medicine, University of Oslo, Oslo, Norway.

PMID: 30397493 PMCID: PMC6203062 DOI: 10.1136/bmjdrc-2018-000569

Abstract

OBJECTIVE: The purpose of this study was to examine the risk of diabetes associated with the presence or absence of chronic low back pain, considering both cross-sectional and cohort data.

RESEARCH DESIGN AND METHODS: Analyses were based on the Norwegian HUNT2 and HUNT3 surveys of Nord-Trøndelag County. The prevalence of diabetes was compared in groups with and without chronic low back pain among 45 157 participants aged 30-69 years. Associations between low back pain at baseline and risk of diabetes were examined in an 11-year follow-up of 30 380 individuals with no baseline diagnosis of diabetes. The comorbidity between diabetes and low back pain was assessed at the end of follow-up. All analyses were carried out considering generalized linear models incorporating adjustment for other relevant risk factors.

RESULTS: Cross-sectional analyses did not reveal any association between low back pain and diabetes. With adjustment for age, body mass index, physical activity and smoking, the cohort study of women showed a significant association between low back pain at baseline and risk of diabetes (RR 1.30; 95%  CI 1.09 to 1.54, p=0.003). The association differed between age groups (p=0.015), with a stronger association in relatively young women. In men, no association was found in the whole age range (RR 1.02; 95%  CI 0.86 to 1.21, p=0.82). No association was observed between diabetes and chronic low back pain at the end of follow-up.

CONCLUSION: Among younger women, those with chronic low back pain may have an increased risk of diabetes.

Keywords: HUNT; cohort; diabetes; low back pain; musculoskeletal disorder

Conflict of interest statement

Competing interests: None declared.

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