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Pedra NS, Galdino KCA, da Silva DS, et al. Endophytic Fungus Isolated From . Front Oncol. 2018;8:476doi: 10.3389/fonc.2018.00476.
Pedra, N. S., Galdino, K. C. A., da Silva, D. S., Ramos, P. T., Bona, N. P., Soares, M. S. P., Azambuja, J. H., Canuto, K. M., de Brito, E. S., Ribeiro, P. R. V., Souza, A. S. Q., Cunico, W., Stefanello, F. M., Spanevello, R. M., & Braganhol, E. (2018). Endophytic Fungus Isolated From . Frontiers in oncology, 8476. https://doi.org/10.3389/fonc.2018.00476
Pedra, Nathalia Stark, et al. "Endophytic Fungus Isolated From ." Frontiers in oncology vol. 8 (2018): 476. doi: https://doi.org/10.3389/fonc.2018.00476
Pedra NS, Galdino KCA, da Silva DS, Ramos PT, Bona NP, Soares MSP, Azambuja JH, Canuto KM, de Brito ES, Ribeiro PRV, Souza ASQ, Cunico W, Stefanello FM, Spanevello RM, Braganhol E. Endophytic Fungus Isolated From . Front Oncol. 2018 Oct 29;8:476. doi: 10.3389/fonc.2018.00476. eCollection 2018. PMID: 30420941; PMCID: PMC6215846.
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Front Oncol. 2018 Oct 29;8:476. doi: 10.3389/fonc.2018.00476. eCollection 2018.

Endophytic Fungus Isolated From .

Frontiers in oncology

Nathalia Stark Pedra, Kennia de Cássia Araújo Galdino, Daniel Schuch da Silva, Priscila Treptow Ramos, Natália Pontes Bona, Mayara Sandrielly Pereira Soares, Juliana Hoffstater Azambuja, Kirley Marques Canuto, Edy Sousa de Brito, Paulo Riceli Vasconcelos Ribeiro, Ana Sheila de Queiroz Souza, Wilson Cunico, Francieli Moro Stefanello, Roselia Maria Spanevello, Elizandra Braganhol

Affiliations

  1. Programa de Pós-Graduação em Bioquímica e Bioprospecção, Centro de Ciências Químicas, Farmacêuticas e de Alimentos, Universidade Federal de Pelotas, Pelotas, Brazil.
  2. Departamento de Ciências Básicas da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.
  3. Embrapa Agroindústria Tropical, Fortaleza, Brazil.

PMID: 30420941 PMCID: PMC6215846 DOI: 10.3389/fonc.2018.00476

Abstract

Glioblastoma is the most devastating primary brain tumor. Current treatment is palliative, making necessary the development of new therapeutic strategies to offer alternatives to patients. Therefore, endophytes represent an interesting source of natural metabolites with anticancer potential. These microorganisms reside in tissues of living plants and act to improve their growth. Evidence revealed that several medicinal plants are colonized by endophytic fungi producer of antitumor metabolites.

Keywords: Achyrocline satureioides; antineoplasic agent; antioxidant; endophytic fungus; glioblastoma; lactone

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