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De Coster T, Claus P, Seemann G, et al. Myocyte Remodeling Due to Fibro-Fatty Infiltrations Influences Arrhythmogenicity. Front Physiol. 2018;9:1381doi: 10.3389/fphys.2018.01381.
De Coster, T., Claus, P., Seemann, G., Willems, R., Sipido, K. R., & Panfilov, A. V. (2018). Myocyte Remodeling Due to Fibro-Fatty Infiltrations Influences Arrhythmogenicity. Frontiers in physiology, 91381. https://doi.org/10.3389/fphys.2018.01381
De Coster, Tim, et al. "Myocyte Remodeling Due to Fibro-Fatty Infiltrations Influences Arrhythmogenicity." Frontiers in physiology vol. 9 (2018): 1381. doi: https://doi.org/10.3389/fphys.2018.01381
De Coster T, Claus P, Seemann G, Willems R, Sipido KR, Panfilov AV. Myocyte Remodeling Due to Fibro-Fatty Infiltrations Influences Arrhythmogenicity. Front Physiol. 2018 Oct 04;9:1381. doi: 10.3389/fphys.2018.01381. eCollection 2018. PMID: 30344493; PMCID: PMC6182296.
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Front Physiol. 2018 Oct 04;9:1381. doi: 10.3389/fphys.2018.01381. eCollection 2018.

Myocyte Remodeling Due to Fibro-Fatty Infiltrations Influences Arrhythmogenicity.

Frontiers in physiology

Tim De Coster, Piet Claus, Gunnar Seemann, Rik Willems, Karin R Sipido, Alexander V Panfilov

Affiliations

  1. Department of Physics and Astronomy, Ghent University, Ghent, Belgium.
  2. Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium.
  3. Institute for Experimental Cardiovascular Medicine, University Heart Centre Freiburg • Bad Krozingen, Medical Center - University of Freiburg, and Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  4. Laboratory of Experimental Cardiology, Department of Cardiology, Heart Lung Centre Leiden, Leiden University Medical Center, Leiden, Netherlands.
  5. Laboratory of Computational Biology and Medicine, Ural Federal University, Ekaterinburg, Russia.

PMID: 30344493 PMCID: PMC6182296 DOI: 10.3389/fphys.2018.01381

Abstract

The onset of cardiac arrhythmias depends on the electrophysiological and structural properties of cardiac tissue. Electrophysiological remodeling of myocytes due to the presence of adipocytes constitutes a possibly important pathway in the pathogenesis of atrial fibrillation. In this paper we perform an

Keywords: adipose tissue; arrhythmogenicity; atrial fibrillation; computational modeling; ionic modeling

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