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Ultrasound Int Open. 2018 Oct;4(4):E142-E148. doi: 10.1055/a-0684-9483. Epub 2018 Oct 25.

Sonographic Venous Velocity Index Identifies Patients with Chronic Kidney Disease and Severe Diastolic Dysfunction.

Ultrasound international open

Markus Meier, Wolfram Johannes Jabs, Maria Guthmann, Gesa Geppert, Ali Aydin, Martin Nitschke

Affiliations

  1. Nephrology Center Reinbek and Geesthacht, Outpatient Clinic, Reinbek, Germany.
  2. Vivantes Klinikum im Friedrichshain, Nephrology, Berlin, Germany.
  3. Krankenhaus-Reinbek Sankt Adolf-Stift, Cardiology, Reinbek, Germany.
  4. Universitat zu Lubeck Sektion Medizin, Medical Clinic I, Lubeck, Germany.

PMID: 30370402 PMCID: PMC6202069 DOI: 10.1055/a-0684-9483

Abstract

OBJECTIVE: Diagnosing cardiorenal syndrome (CRS) in patients with chronic kidney disease (CKD) continues to remain challenging in outpatient practice. In this study, we investigate whether a newly developed venous velocity ultrasound index (VVI) can differentiate between patients with CRS and patients with CKD of other cause or normal renal function (NRF).

METHODS: Patients with CRS (n

RESULTS: The GFRs of patients with CRS and those with CKD were comparable (26.4±5 and 25.6±7 ml/min/m2), as was the age in patients with CRS and NRF (6 ±12 years and 68±16 years, respectively). There was no significant difference in ejection fraction between patients with CRS and those with CKD (44.2±6.2% vs. 47.4 ±7.2), but there was a significant decrease compared to those with NRF (52.6 ±5.1, p<0.01). The VVI was significantly higher in the CRS group (0.81± 0.18) compared to the CKD group (0.18± 0.17, p<0.01) or NRF group (0.22± 0.20, p<0.01). The positive predictability of CRS was 96.4% in patients with VVI values of >0.6.

CONCLUSION: The newly developed VVI was useful in successfully predicting severe diastolic dysfunction (CRS) in patients with severe kidney injury in outpatient care.

Keywords: cardiorenal syndrome; chronic kidney disease; renal ultrasound; renal venous congestion

References

  1. J Am Coll Cardiol. 2004 Jan 7;43(1):61-7 - PubMed
  2. Eur J Intern Med. 2013 Mar;24(2):177-82 - PubMed
  3. World J Nephrol. 2017 May 6;6(3):123-131 - PubMed
  4. Circulation. 2010 Jun 15;121(23):2592-600 - PubMed
  5. JACC Heart Fail. 2016 Aug;4(8):674-82 - PubMed
  6. J Am Coll Cardiol. 2008 Nov 4;52(19):1527-39 - PubMed
  7. Circ Heart Fail. 2017 Jul;10(7):null - PubMed
  8. Ultraschall Med. 2008 Aug;29(4):344-65; quiz 366-73 - PubMed
  9. Radiology. 2009 Sep;252(3):888-96 - PubMed
  10. Kidney Dis (Basel). 2017 Jan;2(4):151-163 - PubMed
  11. Semin Nephrol. 2012 Jan;32(1):18-25 - PubMed
  12. J Ultrasound Med. 2017 Aug;36(8):1607-1615 - PubMed
  13. Blood Purif. 2015;40(4):337-43 - PubMed
  14. Transplant Proc. 2017 Nov;49(9):1993-1998 - PubMed
  15. J Hypertens. 2014 Jan;32(1):149-53 - PubMed
  16. JAAPA. 2014 Feb;27(2):12-7 - PubMed
  17. Eur J Intern Med. 2016 May;30:1-6 - PubMed
  18. AJR Am J Roentgenol. 2003 Apr;180(4):885-92 - PubMed
  19. Lancet. 2013 Jul 27;382(9889):339-52 - PubMed
  20. JACC Heart Fail. 2017 Sep;5(9):672-681 - PubMed

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