Display options
Cite
Burroughs Peña MS, Swett K, Kaplan RC, et al. Childhood and adult exposure to secondhand tobacco smoke and cardiac structure and function: results from Echo-SOL. Open Heart. 2018;5(2):e000831doi: 10.1136/openhrt-2018-000831.
Burroughs Peña, M. S., Swett, K., Kaplan, R. C., Perreira, K., Daviglus, M., Kansal, M. M., Cai, J., Giachello, A. L., Gellman, M. D., Velazquez, E. J., & Rodriguez, C. J. (2018). Childhood and adult exposure to secondhand tobacco smoke and cardiac structure and function: results from Echo-SOL. Open heart, 5(2), e000831. https://doi.org/10.1136/openhrt-2018-000831
Burroughs Peña, Melissa Suzanne, et al. "Childhood and adult exposure to secondhand tobacco smoke and cardiac structure and function: results from Echo-SOL." Open heart vol. 5,2 (2018): e000831. doi: https://doi.org/10.1136/openhrt-2018-000831
Burroughs Peña MS, Swett K, Kaplan RC, Perreira K, Daviglus M, Kansal MM, Cai J, Giachello AL, Gellman MD, Velazquez EJ, Rodriguez CJ. Childhood and adult exposure to secondhand tobacco smoke and cardiac structure and function: results from Echo-SOL. Open Heart. 2018 Oct 19;5(2):e000831. doi: 10.1136/openhrt-2018-000831. eCollection 2018. PMID: 30402256; PMCID: PMC6203071.
Copy Download .nbib Format: NLM
Share it on

Open Heart. 2018 Oct 19;5(2):e000831. doi: 10.1136/openhrt-2018-000831. eCollection 2018.

Childhood and adult exposure to secondhand tobacco smoke and cardiac structure and function: results from Echo-SOL.

Open heart

Melissa Suzanne Burroughs Peña, Katrina Swett, Robert C Kaplan, Krista Perreira, Martha Daviglus, Mayank M Kansal, Jianwen Cai, Aida L Giachello, Marc D Gellman, Eric J Velazquez, Carlos J Rodriguez

Affiliations

  1. Stanford Health Care, Oakland, California, USA.
  2. Department of Medicine, Division of Cardiology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
  3. Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA.
  4. Deparment of Social Medicine, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA.
  5. Institute for Minority Health Research, Unverisity of Illinois School of Medicine, Chicago, Illinois, USA.
  6. Department of Medicine, School of Medicine, University of Illinois, Chicago, Illinois, USA.
  7. Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  8. Department of Preventive Medicine, Feinberg School of Medicine, Northwestern Univerisity, Chicago, Illinois, USA.
  9. Department of Psychology, Miller School of Medicine, University of Miami, Miami, Florida, USA.
  10. Department of Medicine, Yale School of Medicine, New Haven, Connecticut, USA.

PMID: 30402256 PMCID: PMC6203071 DOI: 10.1136/openhrt-2018-000831

Abstract

OBJECTIVE: To describe the relationship of household secondhand smoke (SHS) exposure and cardiac structure and function.

METHODS: Participants (n=1069; 68 % female; age 45-74 years) without history of tobacco use, coronary artery disease or severe valvular disease were included. Past childhood (starting at age <13 years), adolescent/adult and current exposure to household SHS was assessed. Survey linear regression analyses were used to model the relationship of SHS exposure and echocardiographic measures of cardiac structure and function, adjusting for covariates (age, sex, study site, alcohol use, physical activity and education).

RESULTS: SHS exposure in childhood only was associated with reduced E/A velocity ratio (β=-0.06 (SE 0.02), p=0.008). SHS exposure in adolescence/adult only was associated with increased left ventricular ejection fraction (LVEF) (1.2 (0.6), p=0.04), left atrial volume index (1.7 (0.8), p=0.04) and decreased isovolumic relaxation time (-0.003 (0.002), p=0.03). SHS exposure in childhood and adolescence/adult was associated with worse left ventricular global longitudinal strain (LVGLS) (two-chamber) (0.8 (0.4), p= 0.049). Compared with individuals who do not live with a tobacco smoker, individuals who currently live with at least one tobacco smoker had reduced LVEF (-1.4 (0.6), p=0.02), LVGLS (average) (0.9 (0.40), p=0.03), medial E' velocity (-0.5 (0.2), p=0.01), E/A ratio (-0.09 (0.03), p=0.003) and right ventricular fractional area change (-0.02 (0.01), p=0.01) with increased isovolumic relaxation time (0.006 (0.003), p=0.04).

CONCLUSIONS: Past and current household exposure to SHS was associated with abnormalities in cardiac systolic and diastolic function. Reducing household SHS exposure may be an opportunity for cardiac dysfunction prevention to reduce the risk of future clinical heart failure.

Keywords: echocardiography; epidemiology; heart failure; tobacco smoke pollution

Conflict of interest statement

Competing interests: None declared.

References

  1. Ann Epidemiol. 2010 Aug;20(8):629-41 - PubMed
  2. J Am Coll Cardiol. 1995 Jul;26(1):211-6 - PubMed
  3. Int J Cardiol. 2015 Nov 15;199:106-15 - PubMed
  4. Public Health. 2012 Apr;126(4):279-85 - PubMed
  5. Oxid Med Cell Longev. 2017;2017:3759186 - PubMed
  6. Prev Med. 2015 Aug;77:35-40 - PubMed
  7. Ethn Dis. 2015 Spring;25(2):180-6 - PubMed
  8. Lancet. 2011 Jan 8;377(9760):139-46 - PubMed
  9. Int J Epidemiol. 2013 Oct;42(5):1371-80 - PubMed
  10. JAMA. 2012 Nov 7;308(17):1775-84 - PubMed
  11. J Am Coll Cardiol. 2009 Aug 11;54(7):618-24 - PubMed
  12. Rev Environ Health. 2011;26(3):187-95 - PubMed
  13. JACC Heart Fail. 2016 Apr;4(4):237-48 - PubMed
  14. J Am Coll Cardiol. 2010 Jan 19;55(3):234-42 - PubMed
  15. BMC Cardiovasc Disord. 2014 Jun 23;14:78 - PubMed
  16. Circ Heart Fail. 2012 Mar 1;5(2):167-75 - PubMed
  17. FASEB J. 2016 Jun;30(6):2115-22 - PubMed
  18. Clin Ter. 2013;164(5):e429-35 - PubMed
  19. Tob Control. 2013 May;22(e1):e16-20 - PubMed
  20. Ann Epidemiol. 2010 Aug;20(8):642-9 - PubMed
  21. Circulation. 2009 Sep 15;120(11):941-8 - PubMed
  22. J Am Coll Cardiol. 2006 Mar 21;47(6):1150-8 - PubMed
  23. J Am Coll Cardiol. 2014 Feb 11;63(5):447-56 - PubMed
  24. Nicotine Tob Res. 2013 Mar;15(3):745-7 - PubMed
  25. Epidemiology. 2010 Mar;21(2):207-14 - PubMed
  26. Circ Heart Fail. 2016 Apr;9(4):e002733 - PubMed
  27. MMWR Morb Mortal Wkly Rep. 2015 Feb 6;64(4):103-8 - PubMed
  28. Circ Cardiovasc Imaging. 2016 Jan;9(1): - PubMed
  29. J Transl Med. 2015 Oct 15;13:327 - PubMed
  30. Am J Public Health. 2001 Sep;91(9):1424-30 - PubMed
  31. Open Heart. 2017 Jun 14;4(2):e000614 - PubMed
  32. Circulation. 2005 May 24;111(20):2684-98 - PubMed
  33. J Am Soc Echocardiogr. 2017 Jul;30(7):647-658.e2 - PubMed
  34. Int J Environ Res Public Health. 2014 Jul 16;11(7):7261-74 - PubMed
  35. Eur J Epidemiol. 2011 Oct;26(10):763-70 - PubMed
  36. Am J Physiol Heart Circ Physiol. 2011 Jan;300(1):H388-96 - PubMed
  37. J Cardiovasc Nurs. 2006 Nov-Dec;21(6):457-62 - PubMed
  38. Matern Child Health J. 2011 May;15(4):460-8 - PubMed
  39. Circulation. 2007 Feb 27;115(8):990-5 - PubMed
  40. PLoS One. 2014 Dec 02;9(12):e113739 - PubMed
  41. Arch Intern Med. 2012 Nov 26;172(21):1635-41 - PubMed
  42. CMAJ. 2010 May 18;182(8):761-7 - PubMed

Publication Types

Grant support