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Marcon M, Cereser L, Girometti R, et al. Liver involvement by multiple myeloma presenting as hypervascular focal lesions in a patient with chronic hepatitis B infection. BJR Case Rep. 2016;2(3):20150013doi: 10.1259/bjrcr.20150013.
Marcon, M., Cereser, L., Girometti, R., Cataldi, P., Volpetti, S., & Bazzocchi, M. (2016). Liver involvement by multiple myeloma presenting as hypervascular focal lesions in a patient with chronic hepatitis B infection. BJR case reports, 2(3), 20150013. https://doi.org/10.1259/bjrcr.20150013
Marcon, Magda, et al. "Liver involvement by multiple myeloma presenting as hypervascular focal lesions in a patient with chronic hepatitis B infection." BJR case reports vol. 2,3 (2016): 20150013. doi: https://doi.org/10.1259/bjrcr.20150013
Marcon M, Cereser L, Girometti R, Cataldi P, Volpetti S, Bazzocchi M. Liver involvement by multiple myeloma presenting as hypervascular focal lesions in a patient with chronic hepatitis B infection. BJR Case Rep. 2016 May 08;2(3):20150013. doi: 10.1259/bjrcr.20150013. eCollection 2016. PMID: 30459962; PMCID: PMC6243346.
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BJR Case Rep. 2016 May 08;2(3):20150013. doi: 10.1259/bjrcr.20150013. eCollection 2016.

Liver involvement by multiple myeloma presenting as hypervascular focal lesions in a patient with chronic hepatitis B infection.

BJR case reports

Magda Marcon, Lorenzo Cereser, Rossano Girometti, Palmina Cataldi, Stefano Volpetti, Massimo Bazzocchi

Affiliations

  1. Department of Medical and Biological Sciences, Institute of Diagnostic Radiology, University of Udine, University Hospital "Santa Maria della Misericordia", Udine, Italy.
  2. Department of Medical and Morphological Sciences, University of Udine, University Hospital "Santa Maria della Misericordia", Udine, Italy.
  3. Department of Experimental and Clinical Sciences, Division of Hematology and Cellular Therapies Unit "Carlo Melzi", University Hospital "Santa Maria della Misericordia", Udine, Italy.

PMID: 30459962 PMCID: PMC6243346 DOI: 10.1259/bjrcr.20150013

Abstract

Extramedullary myeloma refers to the infiltration of neoplastic monoclonal plasma cells in either organs or soft tissues. The disease is clinically and radiologically underestimated compared with the autopsy findings and is usually associated with a more aggressive clinical course and poorer outcome. A minority of patients with extramedullary myeloma show hepatic involvement, usually in the form of diffuse parenchymal infiltration. When focal infiltration is present, variable imaging findings have been described both on CT scan and MRI. We report the case of a 63-year-old male with hepatitis B virus-related liver disease and biopsy-proven multiple myeloma involving the liver, manifesting as hypervascular focal liver lesions on MRI. A brief review of the literature is also proposed.

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