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Nakatake R, Ishizaki M, Miyasaka C, et al. Hepatectomy in a case of hepatocellular carcinoma with constitutional indocyanine green excretory defect. Int J Surg Case Rep. 2018;53:231-234doi: 10.1016/j.ijscr.2018.10.074.
Nakatake, R., Ishizaki, M., Miyasaka, C., Matsui, K., & Kaibori, M. (2018). Hepatectomy in a case of hepatocellular carcinoma with constitutional indocyanine green excretory defect. International journal of surgery case reports, 53231-234. https://doi.org/10.1016/j.ijscr.2018.10.074
Nakatake, Richi, et al. "Hepatectomy in a case of hepatocellular carcinoma with constitutional indocyanine green excretory defect." International journal of surgery case reports vol. 53 (2018): 231-234. doi: https://doi.org/10.1016/j.ijscr.2018.10.074
Nakatake R, Ishizaki M, Miyasaka C, Matsui K, Kaibori M. Hepatectomy in a case of hepatocellular carcinoma with constitutional indocyanine green excretory defect. Int J Surg Case Rep. 2018;53:231-234. doi: 10.1016/j.ijscr.2018.10.074. Epub 2018 Nov 01. PMID: 30428438; PMCID: PMC6232618.
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Int J Surg Case Rep. 2018;53:231-234. doi: 10.1016/j.ijscr.2018.10.074. Epub 2018 Nov 01.

Hepatectomy in a case of hepatocellular carcinoma with constitutional indocyanine green excretory defect.

International journal of surgery case reports

Richi Nakatake, Morihiko Ishizaki, Chika Miyasaka, Kosuke Matsui, Masaki Kaibori

Affiliations

  1. Department of Surgery, Kansai Medical University, 2-5-1, Hirakata, Osaka 573-1010, Japan. Electronic address: [email protected].
  2. Department of Surgery, Kansai Medical University, 2-5-1, Hirakata, Osaka 573-1010, Japan. Electronic address: [email protected].
  3. Department of Pathology and Laboratory Medicine, Kansai Medical University, 2-5-1, Hirakata, Osaka 573-1010, Japan. Electronic address: [email protected].
  4. Department of Surgery, Kansai Medical University, 2-5-1, Hirakata, Osaka 573-1010, Japan. Electronic address: [email protected].
  5. Department of Surgery, Kansai Medical University, 2-5-1, Hirakata, Osaka 573-1010, Japan. Electronic address: [email protected].

PMID: 30428438 PMCID: PMC6232618 DOI: 10.1016/j.ijscr.2018.10.074

Abstract

INTRODUCTION: Constitutional indocyanine green (ICG) excretory defect is extremely rare. The indocyanine green retention rate at15 min (ICGR15) is important for estimating hepatic functional reserve and selection of the appropriate surgical procedure before hepatectomy is performed. Because of the rarity of constitutional ICG excretory defect, its clinical features are not well understood. We report here evaluation and treatment of a patient with such a disorder.

PRESENTATION OF CASE: An 83-year-old man was admitted to hospital with the diagnosis of resectable hepatocellular carcinoma. The preoperative indocyanine green (ICG) retention rate at 15 min was greater than 76.2%. Despite this finding, Child-Pugh classification and

CONCLUSIONS: Constitutional ICG excretory defect is an extremely rare disorder. At present, the indications for surgery for this condition should be comprehensively considered. Findings of liver function tests, such as a general liver function test and GSA liver scintigraphy, are important for treating this disorder.

Copyright © 2018 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Keywords: (99m)Tc-galactosyl human serum albumin (GSA); Constitutional indocyanine green excretory defect; Hepatocellular carcinoma; Liver resection

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