Display options
Cite
Kim DD, Ghorayeb G. Acute Posterior Multifocal Placoid Pigment Epitheliopathy Associated with Gastrointestinal Stromal Tumor and Hurthle Cell Tumor. Case Rep Ophthalmol Med. 2018;2018:1656131doi: 10.1155/2018/1656131.
Kim, D. D., & Ghorayeb, G. (2018). Acute Posterior Multifocal Placoid Pigment Epitheliopathy Associated with Gastrointestinal Stromal Tumor and Hurthle Cell Tumor. Case reports in ophthalmological medicine, 20181656131. https://doi.org/10.1155/2018/1656131
Kim, Daniel D, and Ghorayeb, Ghassan. "Acute Posterior Multifocal Placoid Pigment Epitheliopathy Associated with Gastrointestinal Stromal Tumor and Hurthle Cell Tumor." Case reports in ophthalmological medicine vol. 2018 (2018): 1656131. doi: https://doi.org/10.1155/2018/1656131
Kim DD, Ghorayeb G. Acute Posterior Multifocal Placoid Pigment Epitheliopathy Associated with Gastrointestinal Stromal Tumor and Hurthle Cell Tumor. Case Rep Ophthalmol Med. 2018 Sep 30;2018:1656131. doi: 10.1155/2018/1656131. eCollection 2018. PMID: 30405928; PMCID: PMC6186340.
Copy Download .nbib Format: NLM
Share it on

Case Rep Ophthalmol Med. 2018 Sep 30;2018:1656131. doi: 10.1155/2018/1656131. eCollection 2018.

Acute Posterior Multifocal Placoid Pigment Epitheliopathy Associated with Gastrointestinal Stromal Tumor and Hurthle Cell Tumor.

Case reports in ophthalmological medicine

Daniel D Kim, Ghassan Ghorayeb

Affiliations

  1. Eye Institute, West Virginia University, Morgantown, WV, USA.

PMID: 30405928 PMCID: PMC6186340 DOI: 10.1155/2018/1656131

Abstract

Acute posterior multifocal placoid pigment epitheliopathy (APMPEE) is a chorioretinal inflammatory disease of unknown origin. Patients usually present with a rapid loss of central/paracentral vision over the course of a week in both eyes. The fundus exhibits rapid appearance of multiple deep subretinal yellow-white, flat lesions at the RPE/choriocapillaris level. This in turn causes changes of both the ellipsoid zone and RPE which can result in permanent central vision loss. The pathogenesis is controversial but is associated with a recent viral illness and can involve the central nervous system with concern for cerebral vasculitis. Rare reports of APMPEE associated with systemic vasculitis such as Wegener's granulomatosis and malignancy such as clear cell renal carcinoma have been reported. We report a case of APMPEE with concurrent diagnosis of gastrointestinal stromal tumor and Hurthle cell tumor. While such association may well be coincidental, the near simultaneous presentation raised our suspicion for potential association.

References

  1. Oncology. 2004;66(6):502-9 - PubMed
  2. Retina. 2009 Jul-Aug;29(7):994-1001 - PubMed
  3. Arch Ophthalmol. 1995 Mar;113(3):297-300 - PubMed
  4. J Stroke Cerebrovasc Dis. 2015 Oct;24(10):e295-302 - PubMed
  5. J Ophthalmic Inflamm Infect. 2016 Dec;6(1):22 - PubMed
  6. J Clin Oncol. 2014 May 20;32(15):1563-70 - PubMed
  7. Ophthalmology. 2001 May;108(5):861-8 - PubMed
  8. Retina. 1999;19(4):309-13 - PubMed
  9. Br J Ophthalmol. 1995 Apr;79(4):384-9 - PubMed
  10. Eye (Lond). 2003 May;17(4):542-4 - PubMed
  11. Retina. 2012 Jul;32(7):1403-10 - PubMed

Publication Types