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Bakshi J, Patro SK, Kaur N, et al. Understanding Malignancies of the Thyroid Gland: Institutional Experience. Indian J Otolaryngol Head Neck Surg. 2018;70(4):482-489doi: 10.1007/s12070-018-1492-3.
Bakshi, J., Patro, S. K., Kaur, N., Panda, N. K., & Budhiraja, G. (2018). Understanding Malignancies of the Thyroid Gland: Institutional Experience. Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 70(4), 482-489. https://doi.org/10.1007/s12070-018-1492-3
Bakshi, Jaimanti, et al. "Understanding Malignancies of the Thyroid Gland: Institutional Experience." Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India vol. 70,4 (2018): 482-489. doi: https://doi.org/10.1007/s12070-018-1492-3
Bakshi J, Patro SK, Kaur N, Panda NK, Budhiraja G. Understanding Malignancies of the Thyroid Gland: Institutional Experience. Indian J Otolaryngol Head Neck Surg. 2018 Dec;70(4):482-489. doi: 10.1007/s12070-018-1492-3. Epub 2018 Sep 05. PMID: 30464902; PMCID: PMC6224818.
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Indian J Otolaryngol Head Neck Surg. 2018 Dec;70(4):482-489. doi: 10.1007/s12070-018-1492-3. Epub 2018 Sep 05.

Understanding Malignancies of the Thyroid Gland: Institutional Experience.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

Jaimanti Bakshi, Sourabha Kumar Patro, Navjot Kaur, Naresh Kumar Panda, Grace Budhiraja

Affiliations

  1. 1Department of Otolaryngology and Head Neck Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
  2. Department of Otolaryngology and Head Neck Surgery, All India Institute of Medical Sciences, AIIMS, BASNI, Jodhpur, 342005 India.

PMID: 30464902 PMCID: PMC6224818 DOI: 10.1007/s12070-018-1492-3

Abstract

To study the epidemiological, pathological characters and determine survival in patients diagnosed of having thyroid gland malignancies. Retrospective chart review of patients having thyroid gland malignancies, which were managed by the two senior authors at our tertiary care institute from January 2000 to December 2006, were performed and evaluated in terms of various clinical, operative and histological parameters. Patients in which follow up of at least 10 years are available were included in the study. Survival was enquired telephonically in those patients who got cured and did not consent to come for follow up. Slides were reviewed. Statistical analysis was done using SPSS statistical software. Kaplan-Meier method was used for calculating survival. A total of 182 patients were included in the study. Papillary carcinoma was the commonest malignant lesion with a frequency of 87.91% followed by follicular carcinoma (7.69%), medullary carcinoma (3.29%) and anaplastic carcinoma (1.09%). Female predominance was seen (F:M-5.06:1). The 5 year and 10 year survival rates were 89% and 73% respectively. The most common postoperative squeal was transient hypocalcaemia, seen in (27/182) 15% patients which was followed by permanent hypocalcaemia 16/182 (8.79%), transient recurrent laryngeal nerve paresis 12/182 (6.59%) and permanent recurrent laryngeal nerve palsy 8/182 (4.39%). Thyroid malignancies affect all age groups and have good long term prognosis. Management yields promising results and hence early and adequate treatment is emphasized.

Keywords: Diagnostic disparities in thyroid gland lesions; Differentiated and dedifferentiated thyroid gland cancers; Metastasis in thyroid cancers; Survival in thyroid gland cancers; Thyroid gland malignancies

Conflict of interest statement

Compliance with Ethical StandardsThe authors declare that they have no conflict of interest.

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