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Riku S, Yamamoto T, Kubota Y, et al. Refractory ventricular fibrillation caused by caffeine intoxication. J Cardiol Cases. 2018;18(6):210-212doi: 10.1016/j.jccase.2018.08.003.
Riku, S., Yamamoto, T., Kubota, Y., Ichii, T., Jinno, Y., Suzuki, S., & Murohara, T. (2018). Refractory ventricular fibrillation caused by caffeine intoxication. Journal of cardiology cases, 18(6), 210-212. https://doi.org/10.1016/j.jccase.2018.08.003
Riku, Shuro, et al. "Refractory ventricular fibrillation caused by caffeine intoxication." Journal of cardiology cases vol. 18,6 (2018): 210-212. doi: https://doi.org/10.1016/j.jccase.2018.08.003
Riku S, Yamamoto T, Kubota Y, Ichii T, Jinno Y, Suzuki S, Murohara T. Refractory ventricular fibrillation caused by caffeine intoxication. J Cardiol Cases. 2018 Sep 08;18(6):210-212. doi: 10.1016/j.jccase.2018.08.003. eCollection 2018 Dec. PMID: 30595775; PMCID: PMC6306552.
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J Cardiol Cases. 2018 Sep 08;18(6):210-212. doi: 10.1016/j.jccase.2018.08.003. eCollection 2018 Dec.

Refractory ventricular fibrillation caused by caffeine intoxication.

Journal of cardiology cases

Shuro Riku, Toshihiko Yamamoto, Yoshiaki Kubota, Takeo Ichii, Yasushi Jinno, Susumu Suzuki, Toyoaki Murohara

Affiliations

  1. Department of Cardiology, Handa City Hospital, Handa, Japan.
  2. Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

PMID: 30595775 PMCID: PMC6306552 DOI: 10.1016/j.jccase.2018.08.003

Abstract

A 30-year-old female with no history of cardiac or systemic disease presented with incessant ventricular fibrillation (VF) after an intake of 12 g of over-the-counter caffeine tablets for a suicidal purpose. Her VF was refractory, and repeated defibrillations were needed to attain a recovery of sinus rhythms. We then performed percutaneous cardiopulmonary support and therapeutic hypothermia to stabilize her circulation and prevent anoxic brain damage, respectively. A blood examination revealed an extremely high concentration of caffeine (172 mg/L). She fully recovered 16 days after her admission. Our findings reveal the potentially lethal arrhythmogenic nature of caffeine. <

Keywords: Caffeine intoxication; QTc interval prolongation; Ventricular fibrillation

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