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Tissue Eng Regen Med. 2017 Sep 19;14(5):605-615. doi: 10.1007/s13770-017-0069-7. eCollection 2017 Oct.

Chemokine Receptors Expression in MSCs: Comparative Analysis in Different Sources and Passages.

Tissue engineering and regenerative medicine

Asieh Heirani-Tabasi, Shirin Toosi, Mahdi Mirahmadi, Mohammad Amir Mishan, Hamid Reza Bidkhori, Ahmad Reza Bahrami, Javad Behravan, Hojjat Naderi-Meshkin

Affiliations

  1. Department of stem Cells and Regenerative Medicine Research, ACECR-Khorasan Razavi Branch Institute, Mashhad, 917751436 Iran.
  2. 2Department of Biotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, 917751436 Iran.
  3. 3Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, 917751436 Iran.

PMID: 30603514 PMCID: PMC6171630 DOI: 10.1007/s13770-017-0069-7

Abstract

MSC-based therapy is providing a cure for degenerative diseases with unmet medical need and usually iliac crest bone marrow (ICBM) are being applied in clinics. Alternative sources, including adipose tissue and reamer/irrigator/aspirator hold great potential for isolating MCSs. Here, we compared original MSCs features of adipose tissue (Ad-MSCs) and bone marrow of long-bone (RIA-MSCs) or iliac crest, and the expression of chemokine receptors (including

Keywords: Adipose tissue; Chemokine receptors; Iliac crest bone marrow; Reamer-irrigator-aspirator; Stem cells

Conflict of interest statement

Authors declared no conflict of interest.This work has been approved by the Ethical Committee of ACECR-Khorasan Razavi Branch and all patients included in this study were informed regarding the usage

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