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Shan X, Choi JH, Kim KJ, et al. Adipose Stem Cells with Conditioned Media for Treatment of Acne Vulgaris Scar. Tissue Eng Regen Med. 2018;15(1):49-61doi: 10.1007/s13770-017-0105-7.
Shan, X., Choi, J. H., Kim, K. J., Lee, Y. J., Ryu, Y. H., Lee, S. J., Moon, S. H., & Rhie, J. W. (2018). Adipose Stem Cells with Conditioned Media for Treatment of Acne Vulgaris Scar. Tissue engineering and regenerative medicine, 15(1), 49-61. https://doi.org/10.1007/s13770-017-0105-7
Shan, Xing, et al. "Adipose Stem Cells with Conditioned Media for Treatment of Acne Vulgaris Scar." Tissue engineering and regenerative medicine vol. 15,1 (2018): 49-61. doi: https://doi.org/10.1007/s13770-017-0105-7
Shan X, Choi JH, Kim KJ, Lee YJ, Ryu YH, Lee SJ, Moon SH, Rhie JW. Adipose Stem Cells with Conditioned Media for Treatment of Acne Vulgaris Scar. Tissue Eng Regen Med. 2018 Jan 16;15(1):49-61. doi: 10.1007/s13770-017-0105-7. eCollection 2018 Feb. PMID: 30603534; PMCID: PMC6171636.
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Tissue Eng Regen Med. 2018 Jan 16;15(1):49-61. doi: 10.1007/s13770-017-0105-7. eCollection 2018 Feb.

Adipose Stem Cells with Conditioned Media for Treatment of Acne Vulgaris Scar.

Tissue engineering and regenerative medicine

Xing Shan, Jong Hyeon Choi, Ki Joo Kim, Yoon Jae Lee, Yeon Hee Ryu, Su Jin Lee, Suk-Ho Moon, Jong Won Rhie

Affiliations

  1. 1Department of Plastic and Reconstructive Surgery, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul, 06591 Republic of Korea.
  2. 2Department of Molecular Biomedicine, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul, 06591 Republic of Korea.

PMID: 30603534 PMCID: PMC6171636 DOI: 10.1007/s13770-017-0105-7

Abstract

This study was to investigate the effect of subcutaneous injection of the adipose stem cells (ASCs) with conditioned media (CM) in the treatment of acne vulgaris scar. We used Adult male New Zealand white rabbit ears as an animal model and induced acne formation by Kignman method. Adipose tissue was isolated and harvested from the scapula of rabbits, and ASCs were cultured and expanded until passage 1. There have four groups in our experiment, include phosphate buffered saline (PBS), ASCs with PBS (ASC + PBS), CM, and ASCs with CM (ASC + CM) group. This solution of 0.6 ml injected to subcutaneous in each group. ASC + PBS and ASC + CM groups were containing ASCs of 5.0 × 10

Keywords: Acne scar model; Acne vulgaris scar; Adipose stem cell; Conditioned media; Keratin 16

Conflict of interest statement

The authors declare that they have no conflict of interest.We had used adipose tissue excised from rabbit in our experiment. And the experimental protocol was approved by the Department of Laboratory

References

  1. Stroke. 2000 Jan;31(1):40-7 - PubMed
  2. J Invest Dermatol. 2000 Mar;114(3):602-8 - PubMed
  3. J Invest Dermatol. 2001 May;116(5):633-40 - PubMed
  4. Methods. 2001 Dec;25(4):402-8 - PubMed
  5. J Am Acad Dermatol. 2003 Jul;49(1 Suppl):S1-37 - PubMed
  6. Aesthetic Plast Surg. 2003 Sep-Oct;27(5):397-402 - PubMed
  7. JAMA. 2004 Aug 11;292(6):726-35 - PubMed
  8. Am J Pathol. 2005 Jun;166(6):1691-9 - PubMed
  9. Wound Repair Regen. 1996 Jul-Sep;4(3):321-5 - PubMed
  10. J Dermatol Sci. 2007 Oct;48(1):15-24 - PubMed
  11. Facial Plast Surg Clin North Am. 2007 Aug;15(3):353-60, vi-vii - PubMed
  12. Facial Plast Surg Clin North Am. 2007 Aug;15(3):387-97, vii - PubMed
  13. J Invest Dermatol. 2008 Apr;128(4):846-54 - PubMed
  14. Biol Pharm Bull. 2008 Apr;31(4):606-10 - PubMed
  15. J Dermatol Sci. 2009 Feb;53(2):96-102 - PubMed
  16. Cardiovasc Res. 2009 Feb 15;81(3):474-81 - PubMed
  17. J Am Acad Dermatol. 2009 May;60(5 Suppl):S1-50 - PubMed
  18. Dermatol Surg. 2010 Mar;36(3):299-306 - PubMed
  19. Wound Repair Regen. 2010 Jul-Aug;18(4):409-16 - PubMed
  20. Acta Dermatovenerol Croat. 2010;18(3):190-4 - PubMed
  21. J Drugs Dermatol. 2010 Nov;9(11):1420-6 - PubMed
  22. Mol Biosyst. 2011 Nov;7(11):3006-20 - PubMed
  23. J Clin Aesthet Dermatol. 2011 Aug;4(8):50-7 - PubMed
  24. Ann Dermatol. 2011 Nov;23(4):448-54 - PubMed
  25. Br J Dermatol. 2013 Mar;168(3):474-85 - PubMed
  26. Expert Opin Drug Discov. 2013 Mar;8(3):331-55 - PubMed
  27. J Drugs Dermatol. 2013 Jan;12(1):e7-e13 - PubMed
  28. PLoS One. 2013;8(1):e55640 - PubMed
  29. Int Wound J. 2015 Feb;12(1):10-6 - PubMed
  30. Aesthetic Plast Surg. 2014 Feb;38(1):230-233 - PubMed
  31. PLoS One. 2013 Aug 28;8(8):e72923 - PubMed
  32. Biomed Res Int. 2013;2013:519126 - PubMed
  33. Wound Repair Regen. 2014 May-Jun;22(3):313-25 - PubMed
  34. Cell Biosci. 2014 May 02;4:24 - PubMed
  35. Int J Mol Med. 2015 Jun;35(6):1651-6 - PubMed
  36. Expert Opin Biol Ther. 2015;15(9):1285-92 - PubMed
  37. Food Funct. 2015 Aug;6(8):2550-60 - PubMed
  38. JAAPA. 2015 Jul;28(7):34-9 - PubMed
  39. Postepy Hig Med Dosw (Online). 2015 Jan 02;69:874-85 - PubMed
  40. Exp Ther Med. 2015 Sep;10(3):1194-1198 - PubMed
  41. J Cosmet Laser Ther. 2016 Jun;18(3):138-48 - PubMed
  42. Int J Mol Med. 2016 Mar;37(3):639-48 - PubMed
  43. PLoS One. 2016 Mar 03;11(3):e0150635 - PubMed
  44. Dermatol Surg. 2016 May;42 Suppl 2:S139-49 - PubMed
  45. J Am Acad Dermatol. 1984 Jan;10(1):96-105 - PubMed
  46. Drug Saf. 1993 Oct;9(4):280-90 - PubMed
  47. J Cell Biol. 1996 Feb;132(3):381-97 - PubMed
  48. Science. 1997 Apr 4;276(5309):75-81 - PubMed
  49. Toxicology. 1998 Aug 21;129(2-3):193-200 - PubMed

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