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Front Surg. 2018 Nov 27;5:70. doi: 10.3389/fsurg.2018.00070. eCollection 2018.

Cartilage Tissue Engineering Using Stem Cells and Bioprinting Technology-Barriers to Clinical Translation.

Frontiers in surgery

Sam L Francis, Claudia Di Bella, Gordon G Wallace, Peter F M Choong

Affiliations

  1. Department of Surgery, University of Melbourne, Melbourne, VIC, Australia.
  2. Department of Orthopaedics, St Vincent's Hospital, Melbourne, VIC, Australia.
  3. Biofab 3D, Aikenhead Centre for Medical Discovery, Melbourne, VIC, Australia.
  4. Australian Research Council, Centre of Excellence for Electromaterials Science, Intelligent Polymer Research Institute, University of Wollongong, Wollongong, NSW, Australia.

PMID: 30547034 PMCID: PMC6278684 DOI: 10.3389/fsurg.2018.00070

Abstract

There is no long-term treatment strategy for young and active patients with cartilage defects. Early and effective joint preserving treatments in these patients are crucial in preventing the development of osteoarthritis. Tissue engineering over the past few decades has presented hope in overcoming the issues involved with current treatment strategies. Novel advances in 3D bioprinting technology have promoted more focus on efficient delivery of engineered tissue constructs. There have been promising

Keywords: bio fabrication; bioprinting; cartilage; hydrogels; scaffolds; stem cells; tissue engineering

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