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Memisoglu G, Gulbahar B, Zubia J, et al. Theoretical Modeling of Viscosity Monitoring with Vibrating Resonance Energy Transfer for Point-of-Care and Environmental Monitoring Applications. Micromachines (Basel). 2018;10(1)doi: 10.3390/mi10010003.
Memisoglu, G., Gulbahar, B., Zubia, J., & Villatoro, J. (2018). Theoretical Modeling of Viscosity Monitoring with Vibrating Resonance Energy Transfer for Point-of-Care and Environmental Monitoring Applications. Micromachines, 10(1), . https://doi.org/10.3390/mi10010003
Memisoglu, Gorkem, et al. "Theoretical Modeling of Viscosity Monitoring with Vibrating Resonance Energy Transfer for Point-of-Care and Environmental Monitoring Applications." Micromachines vol. 10,1 (2018). doi: https://doi.org/10.3390/mi10010003
Memisoglu G, Gulbahar B, Zubia J, Villatoro J. Theoretical Modeling of Viscosity Monitoring with Vibrating Resonance Energy Transfer for Point-of-Care and Environmental Monitoring Applications. Micromachines (Basel). 2018 Dec 21;10(1). doi: 10.3390/mi10010003. PMID: 30577634; PMCID: PMC6356408.
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Micromachines (Basel). 2018 Dec 21;10(1). doi: 10.3390/mi10010003.

Theoretical Modeling of Viscosity Monitoring with Vibrating Resonance Energy Transfer for Point-of-Care and Environmental Monitoring Applications.

Micromachines

Gorkem Memisoglu, Burhan Gulbahar, Joseba Zubia, Joel Villatoro

Affiliations

  1. Department of Communications Engineering, Escuela de Ingeniería de Bilbao, University of the Basque Country (UPV/EHU), Alda. Urquijo s/n, E-48013 Bilbao, Spain. [email protected].
  2. Department of Electrical and Electronics Engineering, Ozyegin University, 34794 Istanbul, Turkey. [email protected].
  3. Department of Communications Engineering, Escuela de Ingeniería de Bilbao, University of the Basque Country (UPV/EHU), Alda. Urquijo s/n, E-48013 Bilbao, Spain. [email protected].
  4. Department of Communications Engineering, Escuela de Ingeniería de Bilbao, University of the Basque Country (UPV/EHU), Alda. Urquijo s/n, E-48013 Bilbao, Spain. [email protected].
  5. IKERBASQUE?Basque Foundation for Science, E-48011 Bilbao, Spain. [email protected].

PMID: 30577634 PMCID: PMC6356408 DOI: 10.3390/mi10010003

Abstract

Förster resonance energy transfer (FRET) between two molecules in nanoscale distances is utilized in significant number of applications including biological and chemical applications, monitoring cellular activities, sensors, wireless communications and recently in nanoscale microfluidic radar design denoted by the vibrating FRET (VFRET) exploiting hybrid resonating graphene membrane and FRET design. In this article, a low hardware complexity and novel microfluidic viscosity monitoring system architecture is presented by exploiting VFRET in a novel microfluidic system design. The donor molecules in a microfluidic channel are acoustically vibrated resulting in VFRET in the case of nearby acceptor molecules detected with their periodic optical emission signals. VFRET does not require complicated hardware by directly utilizing molecular interactions detected with the conventional photodetectors. The proposed viscosity measurement system design is theoretically modeled and numerically simulated while the experimental challenges are discussed. It promises point-of-care and environmental monitoring applications including viscosity characterization of blood or polluted water.

Keywords: environmental monitoring; fluidic characterization; förster resonance energy transfer (FRET); microfluidics; point-of-care; viscosity monitoring

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