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McIlwraith EK, Loganathan N, Belsham DD. Phoenixin Expression Is Regulated by the Fatty Acids Palmitate, Docosahexaenoic Acid and Oleate, and the Endocrine Disrupting Chemical Bisphenol A in Immortalized Hypothalamic Neurons. Front Neurosci. 2018;12:838doi: 10.3389/fnins.2018.00838.
McIlwraith, E. K., Loganathan, N., & Belsham, D. D. (2018). Phoenixin Expression Is Regulated by the Fatty Acids Palmitate, Docosahexaenoic Acid and Oleate, and the Endocrine Disrupting Chemical Bisphenol A in Immortalized Hypothalamic Neurons. Frontiers in neuroscience, 12838. https://doi.org/10.3389/fnins.2018.00838
McIlwraith, Emma K, et al. "Phoenixin Expression Is Regulated by the Fatty Acids Palmitate, Docosahexaenoic Acid and Oleate, and the Endocrine Disrupting Chemical Bisphenol A in Immortalized Hypothalamic Neurons." Frontiers in neuroscience vol. 12 (2018): 838. doi: https://doi.org/10.3389/fnins.2018.00838
McIlwraith EK, Loganathan N, Belsham DD. Phoenixin Expression Is Regulated by the Fatty Acids Palmitate, Docosahexaenoic Acid and Oleate, and the Endocrine Disrupting Chemical Bisphenol A in Immortalized Hypothalamic Neurons. Front Neurosci. 2018 Nov 15;12:838. doi: 10.3389/fnins.2018.00838. eCollection 2018. PMID: 30524225; PMCID: PMC6262291.
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Front Neurosci. 2018 Nov 15;12:838. doi: 10.3389/fnins.2018.00838. eCollection 2018.

Phoenixin Expression Is Regulated by the Fatty Acids Palmitate, Docosahexaenoic Acid and Oleate, and the Endocrine Disrupting Chemical Bisphenol A in Immortalized Hypothalamic Neurons.

Frontiers in neuroscience

Emma K McIlwraith, Neruja Loganathan, Denise D Belsham

Affiliations

  1. Department of Physiology, University of Toronto, Toronto, ON, Canada.
  2. Department of Obstetrics and Gynaecology, University of Toronto, Toronto, ON, Canada.
  3. Department of Medicine, University of Toronto, Toronto, ON, Canada.

PMID: 30524225 PMCID: PMC6262291 DOI: 10.3389/fnins.2018.00838

Abstract

Phoenixin (PNX) is a newly identified reproductive peptide required for the estrous cycle. It is most highly expressed in the hypothalamus, where it is a positive regulator of gonadotropin-releasing hormone (GnRH) and kisspeptin. However, it is unknown what signals lie upstream of

Keywords: endocrine-disrupting chemical bisphenol A; fatty acids; gene expression; hypothalamus; phoenixin; signal transduction

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