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Fehniger J, Schiff PB, Pothuri B. Successful treatment of platinum refractory ovarian clear cell carcinoma with secondary cytoreductive surgery and implantable transponder placement to facilitate targeted volumetric arc radiation therapy. Gynecol Oncol Rep. 2018;27:11-14doi: 10.1016/j.gore.2018.11.004.
Fehniger, J., Schiff, P. B., & Pothuri, B. (2019). Successful treatment of platinum refractory ovarian clear cell carcinoma with secondary cytoreductive surgery and implantable transponder placement to facilitate targeted volumetric arc radiation therapy. Gynecologic oncology reports, 2711-14. https://doi.org/10.1016/j.gore.2018.11.004
Fehniger, Julia, et al. "Successful treatment of platinum refractory ovarian clear cell carcinoma with secondary cytoreductive surgery and implantable transponder placement to facilitate targeted volumetric arc radiation therapy." Gynecologic oncology reports vol. 27 (2019): 11-14. doi: https://doi.org/10.1016/j.gore.2018.11.004
Fehniger J, Schiff PB, Pothuri B. Successful treatment of platinum refractory ovarian clear cell carcinoma with secondary cytoreductive surgery and implantable transponder placement to facilitate targeted volumetric arc radiation therapy. Gynecol Oncol Rep. 2018 Nov 17;27:11-14. doi: 10.1016/j.gore.2018.11.004. eCollection 2019 Feb. PMID: 30555884; PMCID: PMC6275169.
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Gynecol Oncol Rep. 2018 Nov 17;27:11-14. doi: 10.1016/j.gore.2018.11.004. eCollection 2019 Feb.

Successful treatment of platinum refractory ovarian clear cell carcinoma with secondary cytoreductive surgery and implantable transponder placement to facilitate targeted volumetric arc radiation therapy.

Gynecologic oncology reports

Julia Fehniger, Peter B Schiff, Bhavana Pothuri

Affiliations

  1. New York University Langone Health, Division of Gynecologic Oncology, 240 East 38th Street, New York, NY, USA.
  2. New York University Langone Health, Department of Radiation Oncology, 160 East 34th Street, New York, NY, USA.

PMID: 30555884 PMCID: PMC6275169 DOI: 10.1016/j.gore.2018.11.004

Abstract

We describe a case of the first successful treatment of platinum refractory clear cell ovarian cancer with secondary cytoreductive surgery and placement of Calypso transponders to facilitate post-operative volumetric arc radiation therapy. In the setting of both primary and recurrent disease, patients with clear cell ovarian cancer are less responsive to standard chemotherapy and those treated with radiation therapy may have improved outcomes compared to the use of other treatment modalities. Volumetric arc radiation therapy with implantable transponders is feasible, and allows for the targeted treatment of sites of metastatic disease while limiting toxicity to surrounding structures and can be considered for patients with recurrent ovarian cancer and oligometastatic disease.

Keywords: Clear cell carcinoma; Ovarian carcinoma; Pelvic radiation; Volumetric arc therapy

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