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Passias PG, Bortz C, Alas H, et al. Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013. J Orthop. 2018;16(1):36-40doi: 10.1016/j.jor.2018.12.011.
Passias, P. G., Bortz, C., Alas, H., Segreto, F. A., Horn, S. R., Ihejirika, Y. U., Vasquez-Montes, D., Pierce, K. E., Brown, A. E., Shenoy, K., DelSole, E. M., Johnson, B., Oh, C., Zhou, P. L., Deflorimonte, C., Dhillon, E. S., Jankowski, P. P., Diebo, B. G., Lafage, V., Lafage, R., Vira, S. N., Bendo, J. A., Goldstein, J. A., Schwab, F. J., & Gerling, M. C. (2019). Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013. Journal of orthopaedics, 16(1), 36-40. https://doi.org/10.1016/j.jor.2018.12.011
Passias, Peter G, et al. "Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013." Journal of orthopaedics vol. 16,1 (2019): 36-40. doi: https://doi.org/10.1016/j.jor.2018.12.011
Passias PG, Bortz C, Alas H, Segreto FA, Horn SR, Ihejirika YU, Vasquez-Montes D, Pierce KE, Brown AE, Shenoy K, DelSole EM, Johnson B, Oh C, Zhou PL, Deflorimonte C, Dhillon ES, Jankowski PP, Diebo BG, Lafage V, Lafage R, Vira SN, Bendo JA, Goldstein JA, Schwab FJ, Gerling MC. Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013. J Orthop. 2018 Dec 20;16(1):36-40. doi: 10.1016/j.jor.2018.12.011. eCollection 2019. PMID: 30662235; PMCID: PMC6324756.
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J Orthop. 2018 Dec 20;16(1):36-40. doi: 10.1016/j.jor.2018.12.011. eCollection 2019.

Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013.

Journal of orthopaedics

Peter G Passias, Cole Bortz, Haddy Alas, Frank A Segreto, Samantha R Horn, Yael U Ihejirika, Dennis Vasquez-Montes, Katherine E Pierce, Avery E Brown, Kartik Shenoy, Edward M DelSole, Bradley Johnson, Cheongeun Oh, Peter L Zhou, Chloe Deflorimonte, Ekhamjeet S Dhillon, Pawel P Jankowski, Bassel G Diebo, Virginie Lafage, Renaud Lafage, Shaleen N Vira, John A Bendo, Jeffrey A Goldstein, Frank J Schwab, Michael C Gerling

Affiliations

  1. Department of Orthopedic Surgery, NYU Langone Orthopedic Hospital, New York, NY, USA.
  2. Department of Orthopedic Surgery, University of Washington, Seattle, WA, USA.
  3. Department of Orthopedic Surgery, SUNY Downstate Medical Center, Brooklyn, NY, USA.
  4. Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY, USA.

PMID: 30662235 PMCID: PMC6324756 DOI: 10.1016/j.jor.2018.12.011

Abstract

INTRODUCTION: This study assessed the incidence and risk factors for pseudarthrosis among primary spine fusion patients.

METHODS: Retrospective review of ACS-NSQIP (2005-2013). Differences in comorbidities between spine fusion patients with and without pseudarthrosis (Pseud, N-Pseud) were assessed using chi-squared tests and Independent Samples

RESULTS: 52,402 patients (57yrs, 53%F, 0.4% w/pseudarthrosis). Alcohol consumption (OR:2.6[1.2-5.7]) and prior history of surgical revision (OR:1.6[1.4-1.8]) were risk factors for pseudarthrosis operation. Pseud patients at higher risk for deep incisional SSI (at 30-days:OR:6.6[2.0-21.8]). Pseud patients had more perioperative complications (avg:0.24 ± 0.43v0.18 ± 0.39,

CONCLUSIONS: Alcoholism and surgical revision are major risk factors for pseudarthrosis in patients undergoing spine fusion.

Keywords: 30-Day complication rates; Alcoholism; Predictors; Primary spine fusion; Pseudarthrosis; Surgical revision

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