Display options
Cite
Keustermans W, Huysmans T, Danckaers F, et al. High quality statistical shape modelling of the human nasal cavity and applications. R Soc Open Sci. 2018;5(12):181558doi: 10.1098/rsos.181558.
Keustermans, W., Huysmans, T., Danckaers, F., Zarowski, A., Schmelzer, B., Sijbers, J., & Dirckx, J. J. J. (2018). High quality statistical shape modelling of the human nasal cavity and applications. Royal Society open science, 5(12), 181558. https://doi.org/10.1098/rsos.181558
Keustermans, William, et al. "High quality statistical shape modelling of the human nasal cavity and applications." Royal Society open science vol. 5,12 (2018): 181558. doi: https://doi.org/10.1098/rsos.181558
Keustermans W, Huysmans T, Danckaers F, Zarowski A, Schmelzer B, Sijbers J, Dirckx JJJ. High quality statistical shape modelling of the human nasal cavity and applications. R Soc Open Sci. 2018 Dec 19;5(12):181558. doi: 10.1098/rsos.181558. eCollection 2018 Dec. PMID: 30662757; PMCID: PMC6304114.
Copy Download .nbib Format: NLM
Share it on

R Soc Open Sci. 2018 Dec 19;5(12):181558. doi: 10.1098/rsos.181558. eCollection 2018 Dec.

High quality statistical shape modelling of the human nasal cavity and applications.

Royal Society open science

William Keustermans, Toon Huysmans, Femke Danckaers, Andrzej Zarowski, Bert Schmelzer, Jan Sijbers, Joris J J Dirckx

Affiliations

  1. Physics Department, University of Antwerp, Laboratory of Biophysics and Biomedical Physics, Groenenborgerlaan 171, 2020 Antwerp, Belgium.
  2. Faculty of Industrial Design Engineering, TU Delft, Landbergstraat 15, 2628 CE Delft, The Netherlands.
  3. Physics Department, University of Antwerp, Imec-Vision Lab, Edegemsesteenweg 200-240, 2610 Antwerp, Belgium.
  4. ENT Department, GZA Sint-Augustinus Hospital, Oosterveldlaan 24, 2610 Antwerp, Belgium.
  5. ENT Department, ZNA Middelheim Hospital, Lindendreef 1, 2020 Antwerp, Belgium.

PMID: 30662757 PMCID: PMC6304114 DOI: 10.1098/rsos.181558

Abstract

The human nose is a complex organ that shows large morphological variations and has many important functions. However, the relation between shape and function is not yet fully understood. In this work, we present a high quality statistical shape model of the human nose based on clinical CT data of 46 patients. A technique based on cylindrical parametrization was used to create a correspondence between the nasal shapes of the population. Applying principal component analysis on these corresponded nasal cavities resulted in an average nasal geometry and geometrical variations, known as principal components, present in the population with a high precision. The analysis led to 46 principal components, which account for 95% of the total geometrical variation captured. These variations are first discussed qualitatively, and the effect on the average nasal shape of the first five principal components is visualized. Hereafter, by using this statistical shape model, two application examples that lead to quantitative data are shown: nasal shape in function of age and gender, and a morphometric analysis of different anatomical regions. Shape models, as the one presented here, can help to get a better understanding of nasal shape and variation, and their relationship with demographic data.

Keywords: age; cylindrical parametrization; gender; geometry average; morphology; nose

Conflict of interest statement

We declare we have no competing interests.

References

  1. Laryngoscope. 2000 Mar;110(3 Pt 1):417-21 - PubMed
  2. Toxicol Sci. 2001 Nov;64(1):100-10 - PubMed
  3. IEEE Trans Med Imaging. 2002 May;21(5):525-37 - PubMed
  4. J Drug Target. 2002 Jun;10(4):285-96 - PubMed
  5. Laryngoscope. 2003 Jul;113(7):1118-22 - PubMed
  6. Inf Process Med Imaging. 2003 Jul;18:51-62 - PubMed
  7. Am J Hum Biol. 2004 Nov-Dec;16(6):625-38 - PubMed
  8. Clin Otolaryngol Allied Sci. 2004 Dec;29(6):659-66 - PubMed
  9. Toxicol Pathol. 2006;34(3):270-3 - PubMed
  10. Ann Biomed Eng. 2006 Jun;34(6):997-1007 - PubMed
  11. J Aerosol Med. 2006 Fall;19(3):301-13 - PubMed
  12. J Appl Physiol (1985). 2009 Mar;106(3):784-95 - PubMed
  13. Am J Phys Anthropol. 1991 Aug;85(4):419-27 - PubMed
  14. Med Image Anal. 2009 Aug;13(4):543-63 - PubMed
  15. Inhal Toxicol. 2010 Mar;22(4):277-86 - PubMed
  16. IEEE Trans Pattern Anal Mach Intell. 2010 Apr;32(4):636-51 - PubMed
  17. Am J Phys Anthropol. 2011 Aug;145(4):599-614 - PubMed
  18. Ann Biomed Eng. 2012 May;40(5):1142-59 - PubMed
  19. Respir Physiol Neurobiol. 2014 Jan 1;190:54-61 - PubMed
  20. Otolaryngol Head Neck Surg. 2014 Jan;150(1):139-47 - PubMed
  21. Int Forum Allergy Rhinol. 2014 Apr;4(4):298-308 - PubMed
  22. Int Forum Allergy Rhinol. 2014 Jun;4(6):435-46 - PubMed
  23. Acta Otolaryngol. 2014 May;134(5):513-9 - PubMed
  24. J Biomech. 2016 Feb 8;49(3):450-7 - PubMed
  25. Respir Physiol Neurobiol. 2016 Oct;232:66-74 - PubMed
  26. BMC Med Imaging. 2016 Oct 1;16(1):55 - PubMed
  27. Otolaryngol Head Neck Surg. 2017 Apr;156(4):741-750 - PubMed
  28. Eur Respir J. 1996 Feb;9(2):371-6 - PubMed

Publication Types