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Gu ZC, Shi FH, Zhu J, et al. The Management of Heavy Menstrual Bleeding After Percutaneous Coronary Intervention in a Woman of Reproductive Age. Front Pharmacol. 2019;9:1573doi: 10.3389/fphar.2018.01573.
Gu, Z. C., Shi, F. H., Zhu, J., Wan, F., Shen, L., & Li, H. (2018). The Management of Heavy Menstrual Bleeding After Percutaneous Coronary Intervention in a Woman of Reproductive Age. Frontiers in pharmacology, 91573. https://doi.org/10.3389/fphar.2018.01573
Gu, Zhi-Chun, et al. "The Management of Heavy Menstrual Bleeding After Percutaneous Coronary Intervention in a Woman of Reproductive Age." Frontiers in pharmacology vol. 9 (2018): 1573. doi: https://doi.org/10.3389/fphar.2018.01573
Gu ZC, Shi FH, Zhu J, Wan F, Shen L, Li H. The Management of Heavy Menstrual Bleeding After Percutaneous Coronary Intervention in a Woman of Reproductive Age. Front Pharmacol. 2019 Jan 15;9:1573. doi: 10.3389/fphar.2018.01573. eCollection 2018. PMID: 30697160; PMCID: PMC6341068.
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Front Pharmacol. 2019 Jan 15;9:1573. doi: 10.3389/fphar.2018.01573. eCollection 2018.

The Management of Heavy Menstrual Bleeding After Percutaneous Coronary Intervention in a Woman of Reproductive Age.

Frontiers in pharmacology

Zhi-Chun Gu, Fang-Hong Shi, Jie Zhu, Fang Wan, Long Shen, Hao Li

Affiliations

  1. Department of Pharmacy, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
  2. Department of Obstetrics and Gynecology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
  3. Department of Cardiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
  4. Department of Pharmacy, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

PMID: 30697160 PMCID: PMC6341068 DOI: 10.3389/fphar.2018.01573

Abstract

Heavy menstrual bleeding (HMB), previously known as menorrhagia, is in place with heavy flow and longer lasting days of bleeding during menstrual period, sequentially leading to anemia. We reported a rare case of HMB in a 33-year-old patient after percutaneous coronary intervention (PCI), who presented with acute coronary syndromes (ACS), uremia and systemic lupus erythematosus before PCI. This patient received three times of hemodialysis weekly (Monday, Wednesday, and Friday). On the next day after PCI, this patient began to have menstruation. On the fifth day of menstruation, the patient complained of HMB and physical discomfort, with an urgent need for consultation of gynecologist. After gynecologist consultation, this patient was under oxytocin treatment. However, 2 days of oxytocin treatment did not significantly improve HMB. Afterward, the menstrual volume of patients was significantly reduced on eighth day of menstruation after once therapy of testosterone propionate and norethindrone. Regarding the reasons of HMB, heparin in hemodialysis and antiplatelet drugs utilized (aspirin and clopidogrel) after PCI may be contributors to the HMB. In addition, uterine myoma, cervical canal cyst, renal insufficiency and

Keywords: acute coronary syndromes; antiplatelet therapy; heavy menstrual bleeding; menorrhagia; reproductive age; systemic lupus erythematosus; uremia

References

  1. N Engl J Med. 2001 Aug 16;345(7):494-502 - PubMed
  2. Eur J Anaesthesiol. 2006 Jul;23(7):574-9 - PubMed
  3. J Thromb Thrombolysis. 2007 Aug;24(1):39-41 - PubMed
  4. Blood Coagul Fibrinolysis. 2008 Jul;19(5):355-60 - PubMed
  5. J Vet Emerg Crit Care (San Antonio). 2010 Apr 1;20(2):216-23 - PubMed
  6. Int J Gynaecol Obstet. 2011 Apr;113(1):3-13 - PubMed
  7. Am J Surg. 2011 May;201(5):587-91 - PubMed
  8. J Minim Invasive Gynecol. 2011 Jul-Aug;18(4):489-93 - PubMed
  9. BMJ. 2011 Aug 01;343:d4661 - PubMed
  10. JAMA. 2012 Sep 12;308(10):998-1006 - PubMed
  11. Niger J Clin Pract. 2014 Jan-Feb;17(1):10-3 - PubMed
  12. Genet Mol Res. 2015 Feb 13;14(1):1434-42 - PubMed
  13. Maturitas. 2015 Dec;82(4):355-9 - PubMed
  14. Blood. 2016 Mar 17;127(11):1417-25 - PubMed
  15. J Am Coll Cardiol. 2016 Sep 6;68(10):1082-115 - PubMed
  16. Thromb Res. 2017 Mar;151 Suppl 1:S70-S77 - PubMed
  17. Vascul Pharmacol. 2017 Aug;93-95:1-5 - PubMed
  18. Clin Pharmacokinet. 2018 Jul;57(7):817-829 - PubMed
  19. Blood. 2017 Dec 14;130(24):2603-2609 - PubMed
  20. J Atheroscler Thromb. 2018 May 1;25(5):454-459 - PubMed
  21. Thromb Res. 2018 Mar;163:77-82 - PubMed
  22. Can J Cardiol. 2018 Mar;34(3):214-233 - PubMed
  23. Obstet Gynecol. 2018 Apr;131(4):632-634 - PubMed
  24. Am Heart J. 2018 Apr;198:152-159 - PubMed
  25. Circ Res. 2018 Apr 27;122(9):1176-1190 - PubMed
  26. Pharmacogenomics. 2018 May;19(7):621-628 - PubMed
  27. Zhonghua Xin Xue Guan Bing Za Zhi. 2018 Apr 24;46(4):255-266 - PubMed
  28. Front Pharmacol. 2018 May 15;9:490 - PubMed
  29. Pharmacogenomics. 2018 Aug 1;19(12):937-945 - PubMed
  30. Pharmacogenomics. 2018 Aug 1;19(13):1039-1046 - PubMed
  31. Br J Obstet Gynaecol. 1998 Jun;105(6):592-8 - PubMed

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