Proteomics Clin Appl. 2019 Mar;13(2):e1900004. doi: 10.1002/prca.201900004. Epub 2019 Feb 25.

Proteomics for Clinical Assessment of Kidney Disease.

Proteomics. Clinical applications

Alberto Ortiz

PMID: 30768767 DOI: 10.1002/prca.201900004

Abstract

Kidney disease is one of the fastest growing causes of death worldwide, disclosing an unmet clinical need for early diagnosis and optimized risk stratification that allows high risk patient selection for clinical trials and for more intensive nephroprotective interventions in the clinic. The current issue of PROTEOMICS-Clinical Applications contains four manuscripts that explore different aspects of clinical proteomics implementation in the context of acute kidney injury, chronic kidney disease and, more specifically, diabetic kidney disease, and kidney transplantation from a diagnostic and risk stratification point of view. Overall, the evidence discussed suggests that chronic kidney disease is an example where clinical proteomics has become a valuable tool ready for clinical implementation, expected to have a major impact in patient management.

© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

MeSH terms

• Humans
• Kidney Diseases / diagnosis
• Kidney Diseases / metabolism
• Proteomics*

Publication Types

• Journal Article
• Research Support, Non-U.S. Gov't