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Patient Prefer Adherence. 2019 Jan 14;13:145-150. doi: 10.2147/PPA.S166704. eCollection 2019.

Patient-reported outcomes and considerations in the management of COPD: focus on indacaterol/glycopyrronium bromide.

Patient preference and adherence

Erminia Ridolo, Irene Pellicelli, Bruna Gritti, Cristoforo Incorvaia

Affiliations

  1. Allergy and Clinical Immunology, Medicine and Surgery Department, University of Parma, Parma, Italy, [email protected].
  2. Cardiac/Pulmonary Rehabilitation Unit, ASST Pini-CTO, Milan, Italy.

PMID: 30679906 PMCID: PMC6338236 DOI: 10.2147/PPA.S166704

Abstract

Dual bronchodilation with long-acting beta-2 agonists and muscarinic antagonists is recommended in patients with severe to very severe COPD. Among dual bronchodilator combinations, indacaterol/glycopyrronium combination (IGC) received evidence of higher efficacy and good safety compared with monotherapy with either drug as well as with tiotropium. In randomized controlled trials, the primary outcome is usually the change in mean FEV

Keywords: dual bronchodilation; efficacy; long-acting beta-2 agonists; long-acting muscarinic antagonists; patient’s perception; severe COPD

Conflict of interest statement

Disclosure The authors report no conflicts of interest in this work. Dr Cristoforo Incorvaia reports personal fees from Staller-genes Greer, outside the submitted work.

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