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Bahramian A, Falsafi P, Abbasi T, et al. Comparing Serum and Salivary Levels of Vitamin D in Patients with Recurrent Aphthous Stomatitis and Healthy Individuals. J Dent (Shiraz). 2018;19(4):295-300
Bahramian, A., Falsafi, P., Abbasi, T., Ghanizadeh, M., Abedini, M., Kavoosi, F., Kouhsoltani, M., Noorbakhsh, F., Dabbaghi Tabriz, F., Rajaeih, S., & Rezaei, F. (2018). Comparing Serum and Salivary Levels of Vitamin D in Patients with Recurrent Aphthous Stomatitis and Healthy Individuals. Journal of dentistry (Shiraz, Iran), 19(4), 295-300.
Bahramian, Ayla, et al. "Comparing Serum and Salivary Levels of Vitamin D in Patients with Recurrent Aphthous Stomatitis and Healthy Individuals." Journal of dentistry (Shiraz, Iran) vol. 19,4 (2018): 295-300.
Bahramian A, Falsafi P, Abbasi T, Ghanizadeh M, Abedini M, Kavoosi F, Kouhsoltani M, Noorbakhsh F, Dabbaghi Tabriz F, Rajaeih S, Rezaei F. Comparing Serum and Salivary Levels of Vitamin D in Patients with Recurrent Aphthous Stomatitis and Healthy Individuals. J Dent (Shiraz). 2018 Dec;19(4):295-300. PMID: 30680302; PMCID: PMC6338692.
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J Dent (Shiraz). 2018 Dec;19(4):295-300.

Comparing Serum and Salivary Levels of Vitamin D in Patients with Recurrent Aphthous Stomatitis and Healthy Individuals.

Journal of dentistry (Shiraz, Iran)

Ayla Bahramian, Parisa Falsafi, Teymour Abbasi, Milad Ghanizadeh, Mehdi Abedini, Fatemeh Kavoosi, Maryam Kouhsoltani, Fatemeh Noorbakhsh, Fatemeh Dabbaghi Tabriz, Shahin Rajaeih, Farzad Rezaei

Affiliations

  1. Dept. of Oral Medicine, School of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
  2. Dentist, Tabriz, Iran.
  3. Postgraduate Student, Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
  4. Periodontist, Shahrood, Iran.
  5. Dept. of Oral and Maxillofacial Pathology, School of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
  6. Dept. of Periodontology, School of Dentistry, Tabriz Azad University of Medical Sciences, Tabriz, Iran.
  7. Dept. of Operative Dentistry, School of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
  8. Otorhinolaryngologist, Fellow ship of rhinology, Firoozgar hospital, Iran University of Medical Sciences, Tehran, Iran.
  9. Dept. of Oral and Maxillofacial Surgery, Faculty of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran.

PMID: 30680302 PMCID: PMC6338692

Abstract

STATEMENT OF THE PROBLEM: Recurrent aphthous stomatitis (RAS) is the most prevalent ulcerative condition of the oral mucosa. Many studies have emphasized on immunologic factors as the reason of inducing RAS; however, the exact etiologic cause of RAS has not been identified yet. Vitamin D has an endocrine function and regulatory effects on the immune system. It has potential therapeutic effects on autoimmune diseases, psoriasis, and neoplasms. Vitamin D deficiency has been detected in some autoimmune diseases such as rheumatoid arteritis.

PURPOSE: The aim of the present study was to compare the serum and salivary levels of vitamin D in patients with RAS and healthy individuals.

MATERIALS AND METHOD: In this cross sectional study, patients with RAS, referring to the Department of Oral Medicine, Tabriz Faculty of Dentistry, were evaluated after taking medical history, clinical examinations, and completing an informed consent form. The serum and salivary vitamin D levels were compared between case (n=26) and control (n=26) groups.

RESULTS: The mean serum vitamin D levels in the case and control groups were 33.0.7±12.41 and 50.89±9.30 (ng/dL), respectively, with a statistically significant difference (

CONCLUSION: The serum levels of vitamin D in patients with RAS were significantly less than that in healthy individuals; however, there were no significant differences in salivary vitamin D levels between patients with RAS and healthy individuals. In addition, there was a significant and positive correlation between serum and salivary levels of vitamin D in all patients.

Keywords: Recurrent ; Saliva; Vitamin D ; Aphthous Ulcer

Conflict of interest statement

Conflict of Interest: None declared.

References

  1. J Oral Pathol Med. 2005 Jan;34(1):7-12 - PubMed
  2. Tohoku J Exp Med. 2005 Aug;206(4):305-12 - PubMed
  3. Clin Chim Acta. 2007 Aug;383(1-2):30-40 - PubMed
  4. Br J Oral Maxillofac Surg. 2008 Apr;46(3):198-206 - PubMed
  5. Ann Epidemiol. 2009 Feb;19(2):73-8 - PubMed
  6. Clinics (Sao Paulo). 2009;64(7):645-8 - PubMed
  7. Int J Infect Dis. 2010 Mar;14(3):e184-8 - PubMed
  8. Rheumatol Int. 2011 Jul;31(7):911-4 - PubMed
  9. Clin Exp Rheumatol. 2010 Jul-Aug;28(4 Suppl 60):S50-7 - PubMed
  10. Otolaryngol Clin North Am. 2011 Feb;44(1):79-88, v - PubMed
  11. J Oral Maxillofac Pathol. 2011 Sep;15(3):252-6 - PubMed
  12. J Oral Pathol Med. 2012 Sep;41(8):577-83 - PubMed
  13. J Am Dent Assoc. 2012 Apr;143(4):370-6 - PubMed
  14. CMAJ. 2013 Mar 19;185(5):E240 - PubMed
  15. Nutrients. 2013 Jul 05;5(7):2502-21 - PubMed
  16. J Physiol. 1985 Jun;363:323-34 - PubMed
  17. Int J Rheum Dis. 2014 May;17(4):430-4 - PubMed
  18. Arch Immunol Ther Exp (Warsz). 2014 Jun;62(3):205-15 - PubMed
  19. Dent Clin North Am. 2014 Apr;58(2):281-97 - PubMed
  20. Int J Pediatr Otorhinolaryngol. 2014 Jun;78(6):964-8 - PubMed
  21. Int J Nephrol. 2014;2014:742724 - PubMed
  22. Autoimmun Rev. 2015 May;14(5):363-9 - PubMed
  23. Isr Med Assoc J. 2016 Mar-Apr;18(3-4):177-82 - PubMed
  24. Clin Dermatol. 2016 Jul-Aug;34(4):475-81 - PubMed
  25. Vnitr Lek. 2016 Fall;62(9 Suppl 3):121-125 - PubMed
  26. Int J Biochem. 1983;15(9):1175-8 - PubMed

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