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Negash AA, Asrat D, Abebe W, et al. Bacteremic Community-Acquired Pneumonia in Ethiopian Children: Etiology, Antibiotic Resistance, Risk Factors, and Clinical Outcome. Open Forum Infect Dis. 2019;6(3):ofz029doi: 10.1093/ofid/ofz029.
Negash, A. A., Asrat, D., Abebe, W., Hailemariam, T., Hailu, T., Aseffa, A., & Vaneechoutte, M. (2019). Bacteremic Community-Acquired Pneumonia in Ethiopian Children: Etiology, Antibiotic Resistance, Risk Factors, and Clinical Outcome. Open forum infectious diseases, 6(3), ofz029. https://doi.org/10.1093/ofid/ofz029
Negash, Abel Abera, et al. "Bacteremic Community-Acquired Pneumonia in Ethiopian Children: Etiology, Antibiotic Resistance, Risk Factors, and Clinical Outcome." Open forum infectious diseases vol. 6,3 (2019): ofz029. doi: https://doi.org/10.1093/ofid/ofz029
Negash AA, Asrat D, Abebe W, Hailemariam T, Hailu T, Aseffa A, Vaneechoutte M. Bacteremic Community-Acquired Pneumonia in Ethiopian Children: Etiology, Antibiotic Resistance, Risk Factors, and Clinical Outcome. Open Forum Infect Dis. 2019 Jan 23;6(3):ofz029. doi: 10.1093/ofid/ofz029. eCollection 2019 Mar. PMID: 30838226; PMCID: PMC6396085.
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Open Forum Infect Dis. 2019 Jan 23;6(3):ofz029. doi: 10.1093/ofid/ofz029. eCollection 2019 Mar.

Bacteremic Community-Acquired Pneumonia in Ethiopian Children: Etiology, Antibiotic Resistance, Risk Factors, and Clinical Outcome.

Open forum infectious diseases

Abel Abera Negash, Daniel Asrat, Workeabeba Abebe, Tewodros Hailemariam, Tsegaye Hailu, Abraham Aseffa, Mario Vaneechoutte

Affiliations

  1. Armauer Hansen Research Institute, Addis Ababa, Ethiopia.
  2. Laboratory Bacteriology Research, Department of Diagnostic Sciences, Faculty of Medicine & Health Sciences, Ghent University, Ghent, Belgium.
  3. Department of Microbiology and Immunology, School of Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
  4. Department of Pediatrics and Child Health, School of Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
  5. Department of Pediatrics and Child Health, Yekatit 12 Medical College, Addis Ababa, Ethiopia.

PMID: 30838226 PMCID: PMC6396085 DOI: 10.1093/ofid/ofz029

Abstract

BACKGROUND: Community-acquired pneumonia (CAP) remains a leading cause of morbidity and mortality. We sought to determine the magnitude, etiology, and risk factors of CAP in children 5 years after introduction of pneumococcal conjugate vaccine (PCV) 10 in Ethiopia.

METHODS: We conducted a prospective observational study on the bacterial etiology and risk factors of CAP among children aged 0-15 years in 2 pediatric emergency departments in Addis Ababa, Ethiopia. Blood culture, antibiotic susceptibility testing, and amplification of pneumococcal

RESULTS: Out of 643 eligible children, 549 were enrolled. The prevalence of bacteremic pneumonia was 5.6%.

CONCLUSIONS: Five years after the introduction of PCV10 in Ethiopia,

Keywords: Ethiopia; PCV10; Staphylococcus aureus; Streptococcus pneumoniae; bacteremic community-acquired pneumonia

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