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Arch Med Sci. 2019 Mar;15(2):416-423. doi: 10.5114/aoms.2018.76928. Epub 2018 Jul 05.

Expression of tryptophan hydroxylase in gastric mucosa in symptomatic and asymptomatic .

Archives of medical science : AMS

Cezary Chojnacki, Tomasz Popławski, Aleksandra Błońska, Janusz Błasiak, Marek Romanowski, Jan Chojnacki

Affiliations

  1. Department of Clinical Nutrition and Gastroenterological Diagnostics, Medical University of Lodz, Lodz, Poland.
  2. Department of Molecular Genetics, University of Lodz, Lodz, Poland.
  3. Department of Gastroenterology, Medical University of Lodz, Lodz, Poland.

PMID: 30899295 PMCID: PMC6425205 DOI: 10.5114/aoms.2018.76928

Abstract

MATERIAL AND METHODS: Ninety subjects (aged 35-49 years) were enrolled in the study and separated into 3 groups of 30 subjects each. Group I - healthy volunteers without

RESULTS: The expression of this enzyme in antral mucosa was 2.69 ±0.97 in group I, 2.28 ±0.69 in group II (

CONCLUSIONS: Increased expression of TpH-1 in gastric mucosa plays a role in pathogenesis of chronic dyspepsia.

Keywords: Helicobacter pylori; chronic dyspepsia; gastric mucosa; tryptophan hydroxylase

Conflict of interest statement

The authors declare no conflict of interest.

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