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J Clin Transl Res. 2016 Sep 15;2(3):84-90. eCollection 2016 Nov 10.

The role of TNF-α in rheumatoid arthritis: a focus on regulatory T cells.

Journal of clinical and translational research

Mark Farrugia, Byron Baron

Affiliations

  1. Center for Molecular Medicine and Biobanking, Faculty of Medicine and Surgery, University of Malta, Msida, Malta.

PMID: 30873466 PMCID: PMC6410649

Abstract

The autoimmune disorder rheumatoid arthritis (RA) causes chronic inflammation and destruction of joints. T cells are a predominant component of the synovial environment in RA, however the functional role of these cells is not yet fully understood. This is in part due to the fact that the balance and importance of the relation of T

Keywords: TNF-α therapy; joint inflammation; regulatory T cells; rheumatoid arthritis

Conflict of interest statement

The authors declare no conflict of interest.

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