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Clin Case Rep. 2018 Dec 18;7(2):272-274. doi: 10.1002/ccr3.1964. eCollection 2019 Feb.

The first reported case of vincristine-induced unilateral vocal cord palsy in an adult patient with HIV-associated Burkitt-like lymphoma being treated with dose-escalated R-EPOCH.

Clinical case reports

Leena T Rahmat, Philip H Brandt, Syed S Ali

Affiliations

  1. Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Sibley Memorial Hospital Johns Hopkins University Washington District of Columbia.
  2. Department of Hematology and Oncology, D'Amour Center for Cancer Care, Baystate Medical Center University of Massachusetts Springfield Massachusetts.

PMID: 30847188 PMCID: PMC6389462 DOI: 10.1002/ccr3.1964

Abstract

Vincristine-induced vocal cord palsy (VCP) is a rare but critical complication. Prompt recognition of VCP is imperative. Vincristine-induced VCP is reversible, and a complete remission of a lymphoma is still feasible upon withdrawal of vincristine from the chemotherapeutic regimen early in the course of treatment.

Keywords: Rā€EPOCH; lymphoma; vincristine; vocal cord palsy

Conflict of interest statement

The authors declare that there is no conflict of interest.

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