Display options
Cite
Mao S, Luo K, Wang L, et al. Metal-Free C-2-H Alkylation of Quinazolin-4-ones with Alkanes via Cross-Dehydrogenative Coupling. Org Lett. 2019;21(7):2365-2368doi: 10.1021/acs.orglett.9b00638.
Mao, S., Luo, K., Wang, L., Zhao, H. Y., Shergalis, A., Xin, M., Neamati, N., Jin, Y., & Zhang, S. Q. (2019). Metal-Free C-2-H Alkylation of Quinazolin-4-ones with Alkanes via Cross-Dehydrogenative Coupling. Organic letters, 21(7), 2365-2368. https://doi.org/10.1021/acs.orglett.9b00638
Mao, Shuai, et al. "Metal-Free C-2-H Alkylation of Quinazolin-4-ones with Alkanes via Cross-Dehydrogenative Coupling." Organic letters vol. 21,7 (2019): 2365-2368. doi: https://doi.org/10.1021/acs.orglett.9b00638
Mao S, Luo K, Wang L, Zhao HY, Shergalis A, Xin M, Neamati N, Jin Y, Zhang SQ. Metal-Free C-2-H Alkylation of Quinazolin-4-ones with Alkanes via Cross-Dehydrogenative Coupling. Org Lett. 2019 Apr 05;21(7):2365-2368. doi: 10.1021/acs.orglett.9b00638. Epub 2019 Mar 25. PMID: 30907598.
Copy Download .nbib Format: NLM
Share it on

Org Lett. 2019 Apr 05;21(7):2365-2368. doi: 10.1021/acs.orglett.9b00638. Epub 2019 Mar 25.

Metal-Free C-2-H Alkylation of Quinazolin-4-ones with Alkanes via Cross-Dehydrogenative Coupling.

Organic letters

Shuai Mao, Kaixiu Luo, Lu Wang, Hong-Yi Zhao, Andrea Shergalis, Minhang Xin, Nouri Neamati, Yi Jin, San-Qi Zhang

Affiliations

  1. Department of Medicinal Chemistry, School of Pharmacy , Xi'an Jiaotong University , Xi'an 710061 , China.
  2. Department of Medicinal Chemistry, College of Pharmacy , University of Michigan , Ann Arbor , Michigan 48109 , United States.
  3. Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology , Yunnan University , Kunming 650091 , P. R. China.

PMID: 30907598 DOI: 10.1021/acs.orglett.9b00638

Abstract

A practically useful approach for the cross-dehydrogenative coupling of quinazolin-4-one with simple nonactivated alkanes is reported. The products were smoothly formed under mild reaction conditions, within short reaction time at ambient temperature. The formation of new Csp

Publication Types