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Sudhakara P, Sellamuthu I, Aruni AW. Bacterial sialoglycosidases in Virulence and Pathogenesis. Pathogens. 2019;8(1)doi: 10.3390/pathogens8010039.
Sudhakara, P., Sellamuthu, I., & Aruni, A. W. (2019). Bacterial sialoglycosidases in Virulence and Pathogenesis. Pathogens (Basel, Switzerland), 8(1), . https://doi.org/10.3390/pathogens8010039
Sudhakara, Preethi, et al. "Bacterial sialoglycosidases in Virulence and Pathogenesis." Pathogens (Basel, Switzerland) vol. 8,1 (2019). doi: https://doi.org/10.3390/pathogens8010039
Sudhakara P, Sellamuthu I, Aruni AW. Bacterial sialoglycosidases in Virulence and Pathogenesis. Pathogens. 2019 Mar 24;8(1). doi: 10.3390/pathogens8010039. PMID: 30909660; PMCID: PMC6471121.
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Pathogens. 2019 Mar 24;8(1). doi: 10.3390/pathogens8010039.

Bacterial sialoglycosidases in Virulence and Pathogenesis.

Pathogens (Basel, Switzerland)

Preethi Sudhakara, Iyappan Sellamuthu, A Wilson Aruni

Affiliations

  1. Department of Genetic Engineering, SRM Institute of Science and Technology, Chennai 603203, India. [email protected].
  2. Department of Genetic Engineering, SRM Institute of Science and Technology, Chennai 603203, India. [email protected].
  3. School of Medicine, California University of Science and Medicine, San Bernardino, CA 92408, USA. [email protected].
  4. Musculoskeletal disease center, Loma Linda Veterans Affairs, US Department of Veteran Affairs, Loma Linda, CA 92350, USA. [email protected].
  5. Sathyabama Institute of Science and Technology, Chennai 600119, India. [email protected].

PMID: 30909660 PMCID: PMC6471121 DOI: 10.3390/pathogens8010039

Abstract

Human oral microbiome and dysbiotic infections have been recently evidently identified. One of the major reasons for such dysbiosis is impairment of the immune system. Periodontitis is a chronic inflammatory disease affecting the tissues that surround and support the teeth. In the United States., approximately 65 million people are affected by this condition. Its occurrence is also associated with many important systemic diseases such as cardiovascular disease, rheumatoid arthritis, and Alzheimer's disease. Among the most important etiologies of periodontitis is

Keywords: Siglec; pathogenicity; sialic acid; sialidase; sialoglycoprotease; therapeutic target

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