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Archer DL. Enteric Microorganisms in Rheumatoid Diseases: Causative Agents and Possible Mechanisms. J Food Prot. 1985;48(6):538-545doi: 10.4315/0362-028X-48.6.538.
Archer, D. L. (1985). Enteric Microorganisms in Rheumatoid Diseases: Causative Agents and Possible Mechanisms. Journal of food protection, 48(6), 538-545. https://doi.org/10.4315/0362-028X-48.6.538
Archer, Douglas L. "Enteric Microorganisms in Rheumatoid Diseases: Causative Agents and Possible Mechanisms." Journal of food protection vol. 48,6 (1985): 538-545. doi: https://doi.org/10.4315/0362-028X-48.6.538
Archer DL. Enteric Microorganisms in Rheumatoid Diseases: Causative Agents and Possible Mechanisms. J Food Prot. 1985 Jun;48(6):538-545. doi: 10.4315/0362-028X-48.6.538. PMID: 30943591.
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J Food Prot. 1985 Jun;48(6):538-545. doi: 10.4315/0362-028X-48.6.538.

Enteric Microorganisms in Rheumatoid Diseases: Causative Agents and Possible Mechanisms.

Journal of food protection

Douglas L Archer

Affiliations

  1. Division of Microbiology, Food and Drug Administration, Washington, DC 20204.

PMID: 30943591 DOI: 10.4315/0362-028X-48.6.538

Abstract

The role of foodborne enteric pathogens in the development of three seronegative spondarthropathies (ankylosing spondylitis, Reiter's disease and reactive arthritis) is discussed. Although the prevalence of the HLA-B27 antigen in blood-related individuals suggests a genetic predisposition to these diseases, exogenous environmental factors are also indicated. A clinical profile is given to clarify certain relationships of the seronegative arthropathies. Evidence of the involvement of enteric pathogens in the onset of these conditions following gastrointestinal illness is considered along with the interactions of general and molecular mechanisms of the disease processes and the immune response.

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