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Front Microbiol. 2019 Feb 15;10:223. doi: 10.3389/fmicb.2019.00223. eCollection 2019.

Potential of Pectins to Beneficially Modulate the Gut Microbiota Depends on Their Structural Properties.

Frontiers in microbiology

Nadja Larsen, Carlota Bussolo de Souza, Lukasz Krych, Thiago Barbosa Cahú, Maria Wiese, Witold Kot, Karin Meyer Hansen, Andreas Blennow, Koen Venema, Lene Jespersen

Affiliations

  1. Department of Food Science, University of Copenhagen, Copenhagen, Denmark.
  2. Center for Healthy Eating and Food Innovation, Maastricht University - Campus Venlo, Maastricht, Netherlands.
  3. Department of Environmental Science, Aarhus University, Roskilde, Denmark.
  4. CP Kelco ApS, Lille Skensved, Denmark.
  5. Department of Plant and Environmental Sciences, University of Copenhagen, Copenhagen, Denmark.
  6. Beneficial Microbes Consultancy, Wageningen, Netherlands.

PMID: 30828323 PMCID: PMC6384267 DOI: 10.3389/fmicb.2019.00223

Abstract

Pectins are plant cell-wall polysaccharides which can be utilized by commensal bacteria in the gut, exhibiting beneficial properties for the host. Knowledge of the impact of pectins on intestinal bacterial communities is insufficient and limited to a few types of pectins. This study characterized the relationship between the structural properties of pectins and their potential to modulate composition and activity of the gut microbiota in a beneficial way. For this purpose we performed

Keywords: TIM-2 colon model; gut microbiota; pectins; short-chain fatty acids; structure-function relationship

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