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Aryankhesal A, Ghashghaee A, Sardari E, et al. Prevalence of depression in patients with cancer in Iran: a systematic review and meta-analysis. BMJ Support Palliat Care. 2019;doi: 10.1136/bmjspcare-2018-001724.
Aryankhesal, A., Ghashghaee, A., Sardari, E., Mahmoudi, S., Alihosseini, S., Dehnad, A., Roohravan Benis, M., & Gharagozlou, D. (2019). Prevalence of depression in patients with cancer in Iran: a systematic review and meta-analysis. BMJ supportive & palliative care, . https://doi.org/10.1136/bmjspcare-2018-001724
Aryankhesal, Aidin, et al. "Prevalence of depression in patients with cancer in Iran: a systematic review and meta-analysis." BMJ supportive & palliative care vol. (2019). doi: https://doi.org/10.1136/bmjspcare-2018-001724
Aryankhesal A, Ghashghaee A, Sardari E, Mahmoudi S, Alihosseini S, Dehnad A, Roohravan Benis M, Gharagozlou D. Prevalence of depression in patients with cancer in Iran: a systematic review and meta-analysis. BMJ Support Palliat Care. 2019 Apr 04; doi: 10.1136/bmjspcare-2018-001724. Epub 2019 Apr 04. PMID: 30948442.
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BMJ Support Palliat Care. 2019 Apr 04; doi: 10.1136/bmjspcare-2018-001724. Epub 2019 Apr 04.

Prevalence of depression in patients with cancer in Iran: a systematic review and meta-analysis.

BMJ supportive & palliative care

Aidin Aryankhesal, Ahmad Ghashghaee, Elnaz Sardari, Sara Mahmoudi, Samira Alihosseini, Afsaneh Dehnad, Mahshid Roohravan Benis, Dorsa Gharagozlou

Affiliations

  1. Health Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran.
  2. Department of Health Services Management, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran.
  3. Health Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran [email protected].
  4. Student Research Committee, Faculty of Health Management and Information Sciences Branch, Iran University of Medical Sciences, Tehran, Iran.
  5. Department of Foreign Languages, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran.
  6. Department of Biology, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran.

PMID: 30948442 DOI: 10.1136/bmjspcare-2018-001724

Abstract

INTRODUCTION: It is generally accepted that depression, affecting the quality of life, is a serious and common complication in patients with cancer. Given that there is no integrated study on this topic in Iran, the present study sought to investigate the prevalence of depression in patients with cancer by a systematic review and meta-analysis.

METHODS: To meet the study objectives, all English and Persian papers published from 2000 to January 2018 were systematically collected and the data were extracted for analysis.

RESULTS: There were 14 studies which were selected on the basis of the inclusion and exclusion criteria. A total number of 2831 patients with cancer had participated in the studies. The prevalence of depression among Iranian patients with cancer was 35% (95% CI 16% to 70%) based on random effects model. Among various types of cancer, the highest prevalence of depression appeared to patients suffering from breast cancer.

CONCLUSION: The prevalence of depression among patients with cancer in Iran was higher than the developed countries. As depression affects the quality of life of patients with cancer, the results can help policymakers and service providers in planning to reduce the prevalence of depression.

© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Keywords: Iran; cancer; depression; multimorbidity; neoplasms

Conflict of interest statement

Competing interests: None declared.

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