J Allergy Clin Immunol Pract. 2019 Mar;7(3):776-785. doi: 10.1016/j.jaip.2018.12.011.
The journal of allergy and clinical immunology. In practice
Richard Mitchell
PMID: 30832892 DOI: 10.1016/j.jaip.2018.12.011
Hematopoietic stem cell transplantation (HSCT) can provide definitive therapy for patients with primary immunodeficiency disease (PIDD). Modern HSCT techniques and supportive care have significantly improved outcomes for patients with PIDD. This review examines current HSCT practice for PIDD other than severe combined immunodeficiency, and explores indications, risks, and long-term outcomes for this group of challenging diseases.
Crown Copyright © 2018. Published by Elsevier Inc. All rights reserved.
Keywords: Hematopoietic stem cell transplantation; Primary immunodeficiency; Reduced intensity conditioning