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Yin Y, Lee JE, Kim NW, et al. Inhibition of Tumor Growth via Systemic siRNA Delivery Using Reducible Bile Acid-Conjugated Polyethylenimine. Polymers (Basel). 2018;10(9)doi: 10.3390/polym10090953.
Yin, Y., Lee, J. E., Kim, N. W., Lee, J. H., Lim, S. Y., Kim, E. S., Park, J. W., Lee, M. S., & Jeong, J. H. (2018). Inhibition of Tumor Growth via Systemic siRNA Delivery Using Reducible Bile Acid-Conjugated Polyethylenimine. Polymers, 10(9), . https://doi.org/10.3390/polym10090953
Yin, Yue, et al. "Inhibition of Tumor Growth via Systemic siRNA Delivery Using Reducible Bile Acid-Conjugated Polyethylenimine." Polymers vol. 10,9 (2018). doi: https://doi.org/10.3390/polym10090953
Yin Y, Lee JE, Kim NW, Lee JH, Lim SY, Kim ES, Park JW, Lee MS, Jeong JH. Inhibition of Tumor Growth via Systemic siRNA Delivery Using Reducible Bile Acid-Conjugated Polyethylenimine. Polymers (Basel). 2018 Aug 27;10(9). doi: 10.3390/polym10090953. PMID: 30960878; PMCID: PMC6403700.
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Polymers (Basel). 2018 Aug 27;10(9). doi: 10.3390/polym10090953.

Inhibition of Tumor Growth via Systemic siRNA Delivery Using Reducible Bile Acid-Conjugated Polyethylenimine.

Polymers

Yue Yin, Jung Eun Lee, Nak Won Kim, Jong Han Lee, Su Yeon Lim, E Seul Kim, Ji Won Park, Min Sang Lee, Ji Hoon Jeong

Affiliations

  1. School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. [email protected].
  2. School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. [email protected].
  3. School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. [email protected].
  4. School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. [email protected].
  5. School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. [email protected].
  6. School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. [email protected].
  7. School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. [email protected].
  8. School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. [email protected].
  9. School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. [email protected].

PMID: 30960878 PMCID: PMC6403700 DOI: 10.3390/polym10090953

Abstract

RNA interference (RNAi), mediated by small interfering RNA (siRNA), has been considered as a potential therapeutic agent for cancer owing to its ability to suppress target genes in a sequence-specific manner. In this study, a conjugate of the low molecular weight (M

Keywords: deoxycholic acid; disulfide crosslinking; small interfering RNA; stabilized polyplex; systemic gene therapy

Conflict of interest statement

The authors declare no conflict of interest.

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