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Halldorsson H, Orrason AW, Oskarsdottir GN, et al. Improved long-term survival following pulmonary resections for non-small cell lung cancer: results of a nationwide study from Iceland. Ann Transl Med. 2019;7(5):88doi: 10.21037/atm.2019.01.10.
Halldorsson, H., Orrason, A. W., Oskarsdottir, G. N., Petursdottir, A., Fridriksson, B. M., Magnusson, M. K., Jonsson, S., & Gudbjartsson, T. (2019). Improved long-term survival following pulmonary resections for non-small cell lung cancer: results of a nationwide study from Iceland. Annals of translational medicine, 7(5), 88. https://doi.org/10.21037/atm.2019.01.10
Halldorsson, Hannes, et al. "Improved long-term survival following pulmonary resections for non-small cell lung cancer: results of a nationwide study from Iceland." Annals of translational medicine vol. 7,5 (2019): 88. doi: https://doi.org/10.21037/atm.2019.01.10
Halldorsson H, Orrason AW, Oskarsdottir GN, Petursdottir A, Fridriksson BM, Magnusson MK, Jonsson S, Gudbjartsson T. Improved long-term survival following pulmonary resections for non-small cell lung cancer: results of a nationwide study from Iceland. Ann Transl Med. 2019 Mar;7(5):88. doi: 10.21037/atm.2019.01.10. PMID: 31019938; PMCID: PMC6462663.
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Ann Transl Med. 2019 Mar;7(5):88. doi: 10.21037/atm.2019.01.10.

Improved long-term survival following pulmonary resections for non-small cell lung cancer: results of a nationwide study from Iceland.

Annals of translational medicine

Hannes Halldorsson, Andri Wilberg Orrason, Gudrun Nina Oskarsdottir, Astridur Petursdottir, Bjorn Mar Fridriksson, Magnus Karl Magnusson, Steinn Jonsson, Tomas Gudbjartsson

Affiliations

  1. Department of Cardiothoracic Surgery, Landspitali University Hospital, Reykjavik, Iceland.
  2. Department of Pulmonology, Skåne University Hospital, Lund, Sweden.
  3. Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
  4. Department of Pulmonology, Landspitali University Hospital, Reykjavik, Iceland.

PMID: 31019938 PMCID: PMC6462663 DOI: 10.21037/atm.2019.01.10

Abstract

BACKGROUND: We studied the outcome of pulmonary resection with curative intent for non-small cell lung cancer (NSCLC) in a nationwide study covering a 24-year period, focusing on survival.

METHODS: All patients who underwent pulmonary resection for NSCLC in Iceland in the period 1991-2014 were reviewed for demographics, TNM stage and survival. Median length of follow-up was 45 months. Three 8-year periods were compared, overall survival was estimated, and prognostic factors for survival were identified.

RESULTS: Altogether, 652 surgical resections were performed on 644 individuals (52% females): 492 lobectomies (75%), 77 pneumonectomies (12%), and 83 sublobar resections (13%). Mean age increased from 65 to 68 yrs during the study period (P=0.002). The number of cases operated at stage IA increased substantially between the first and last periods (29%

CONCLUSIONS: Survival of patients who have undergone pulmonary resection for NSCLC has improved significantly in Iceland. This may be explained by the increased number of patients diagnosed at lower stages and improved preoperative staging, with fewer understaged patients.

Keywords: Non-small cell lung cancer (NSCLC); long-term survival; outcome; prognosis; pulmonary resection

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

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