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Clin Case Rep. 2019 Mar 18;7(4):821-825. doi: 10.1002/ccr3.2088. eCollection 2019 Apr.

Epithelioid glioblastoma presenting as aphasia in a young adult with ovarian cancer: A case report.

Clinical case reports

Megan M Finneran, Joseph Georges, Michael Kakareka, Ryan Moncman, Miriam Enriquez, Todd Siegal, Gregory Kubicek, Alan Turtz, Steven Yocom, H Warren Goldman, James Barrese

Affiliations

  1. Department of Clinical Medicine Chicago College of Osteopathic Medicine Chicago Illinois.
  2. Department of Neurosurgery Philadelphia College of Osteopathic Medicine Philadelphia Pennsylvania.
  3. Department of Neurosurgery Cooper University Hospital Camden New Jersey.
  4. Department of Pathology Cooper University Hospital Camden New Jersey.
  5. Department of Radiology Cooper University Hospital Camden New Jersey.
  6. Department of Radiation Oncology Cooper University Hospital Camden New Jersey.

PMID: 30997093 PMCID: PMC6452522 DOI: 10.1002/ccr3.2088

Abstract

Our patient's clinical history and preoperative radiographic evaluation suggested central nervous system (CNS) metastatic disease. Ultimately, final pathology revealed epithelioid glioblastoma (eGBM), a newly classified CNS primary tumor. This reinforces the importance of direct tissue sampling and including eGBM on the differential for young patients with histories of systemic cancer presenting with new CNS lesions.

Keywords: IDH wild type; epithelioid; glioblastoma; multiforme

Conflict of interest statement

None declared.

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