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Pappachan LG, Williams A, Sebastian T, et al. Changes in central venous oxygen saturation, lactates, and ST segment changes in a V lead ECG with changes in hemoglobin in neurosurgical patients undergoing craniotomy and tumor excision: A prospective observational study. J Anaesthesiol Clin Pharmacol. 2019;35(1):99-105doi: 10.4103/joacp.JOACP_304_17.
Pappachan, L. G., Williams, A., Sebastian, T., Korula, G., & Singh, G. (2019). Changes in central venous oxygen saturation, lactates, and ST segment changes in a V lead ECG with changes in hemoglobin in neurosurgical patients undergoing craniotomy and tumor excision: A prospective observational study. Journal of anaesthesiology, clinical pharmacology, 35(1), 99-105. https://doi.org/10.4103/joacp.JOACP_304_17
Pappachan, Liby G, et al. "Changes in central venous oxygen saturation, lactates, and ST segment changes in a V lead ECG with changes in hemoglobin in neurosurgical patients undergoing craniotomy and tumor excision: A prospective observational study." Journal of anaesthesiology, clinical pharmacology vol. 35,1 (2019): 99-105. doi: https://doi.org/10.4103/joacp.JOACP_304_17
Pappachan LG, Williams A, Sebastian T, Korula G, Singh G. Changes in central venous oxygen saturation, lactates, and ST segment changes in a V lead ECG with changes in hemoglobin in neurosurgical patients undergoing craniotomy and tumor excision: A prospective observational study. J Anaesthesiol Clin Pharmacol. 2019 Jan-Mar;35(1):99-105. doi: 10.4103/joacp.JOACP_304_17. PMID: 31057249; PMCID: PMC6495604.
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J Anaesthesiol Clin Pharmacol. 2019 Jan-Mar;35(1):99-105. doi: 10.4103/joacp.JOACP_304_17.

Changes in central venous oxygen saturation, lactates, and ST segment changes in a V lead ECG with changes in hemoglobin in neurosurgical patients undergoing craniotomy and tumor excision: A prospective observational study.

Journal of anaesthesiology, clinical pharmacology

Liby G Pappachan, Aparna Williams, Tunny Sebastian, Grace Korula, Georgene Singh

Affiliations

  1. Department of Anesthesiology, Christian Medical College, Vellore, Tamil Nadu, India.

PMID: 31057249 PMCID: PMC6495604 DOI: 10.4103/joacp.JOACP_304_17

Abstract

BACKGROUND AND AIMS: The aim of the study was to observe the trends in central venous oxygen saturation (ScvO

MATERIAL AND METHODS: Seventy-seven consecutive patients undergoing craniotomy at a tertiary care institution were recruited for this study after obtaining written, informed consent. After establishing standard monitoring, anesthesia was induced with standard anesthetic protocol. Hemodynamic parameters such as heart rate, blood pressure (mean, systolic, diastolic), pulse pressure variation (PPV), and physiological parameters such as lactate, ScvO

STATISTICAL ANALYSIS: Comparison of the mean and standard deviation for the hemodynamic parameters was performed between the transfused and nontransfused patient groups. Pearson correlation test was done to assess the correlation between the covariates. Receiver operating characteristic (ROC) curve was constructed for the ScvO

RESULTS: There was a statistically significant positive correlation between the change in ScvO

CONCLUSIONS: We conclude that ScvO

Keywords: Acute blood loss; ST segment changes; central venous oxygen saturation (ScvO2); lactates; transfusion trigger

Conflict of interest statement

There are no conflicts of interest.

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