Indian J Dermatol. 2019 Mar-Apr;64(2):90-96. doi: 10.4103/ijd.IJD_464_17.
Biophysical Measurements and Ultrasonographic Findings in Chronic Dermatitis in Comparison with Uninvolved Skin.
Indian journal of dermatology
Taraneh Yazdanparast, Kamran Yazdani, Philippe Humbert, Alireza Khatami, Saman Ahmad Nasrollahi, Leila Izadi Firouzabadi, Alireza Firooz
Affiliations
Affiliations
- Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran.
- Telemedicine Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
- Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
- Research and Studies Center on the Integument, Department of Dermatology, Clinical Investigation Center, Besançon University Hospital, University of Franche-Comté, Besançon, France.
- Clinical Trial Center, Tehran University of Medical Sciences, Tehran, Iran.
PMID: 30983602
PMCID: PMC6440184 DOI: 10.4103/ijd.IJD_464_17
Abstract
BACKGROUND: Nowadays noninvasive techniques are performed to evaluate the biophysical properties of skin
AIMS: The aim of this study was to evaluate the biophysical and ultrasonographic properties of skin in chronic contact or atopic dermatitis to provide better insight into pathogenesis, diagnosis, and treatment response.
MATERIALS AND METHODS: The stratum corneum hydration, transepidermal water loss (TEWL), pH, erythema, melanin, sebum, friction, temperature, elasticity parameters (R0, R2, and R5), the thickness and echo-density of epidermis, dermis, and subepidermal low-echogenic band (SLEB) were measured on lesional, perilesional, and symmetrical skin of 22 chronic dermatitis patients. The average of perilesional and symmetrical skin values (control) was compared with lesional values.
RESULTS: Stratum corneum hydration (
CONCLUSION: Chronic contact and atopic dermatitis are characterized by certain changes in biophysical and biomechanical properties of the skin. The evaluation of these parameters might be useful in the early diagnosis and assessment of treatment response.
Keywords: Biomechanical properties; biophysical properties; chronic dermatitis; ultrasonography
Conflict of interest statement
There are no conflicts of interest.
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